Ginger protects against vein graft remodeling by precisely modulating ferroptotic stress in vascular smooth muscle cell dedifferentiation

Ginger protects against vein graft remodeling by precisely modulating ferroptotic stress in vascular smooth muscle cell dedifferentiation

Vein graft (VG) failure (VGF) is associated with VG intimal hyperplasia, which is characterized by abnormal accumulation of vascular smooth muscle cells (VSMCs). Most neointimal VSMCs are derived from pre-existing VSMCs via a process of VSMC phenotypic transition, also known as dedifferentiation. Th...

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Bibliographic Details
Main Authors: Xiaoyu Yu, Weiwei Wu, Jingjun Hao, Yuxin Zhou, Deyang Yu, Wei Ding, Xuejuan Zhang, Gaoli Liu, Jianxun Wang
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Vascular smooth muscle cells
Dedifferentiation
Vein graft
Ginger
Ferroptotic stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177924001503
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