Soft Tissue Stabilization of Midcarpal Instability in Ehlers–Danlos Patients Using a Cadaveric Tendon Graft

Summary:. Ehlers–Danlos syndrome (EDS) is a group of hereditary disorders that affects collagen synthesis. In the wrist, pain and midcarpal laxity may affect up to 70% of EDS patients. The mainstay treatment of midcarpal instability in patients with ligamentous injury but not EDS includes orthotics,...

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Main Authors: Mohammed Muneer, MD, Fadi Bouri, MBBS, Kjell Van Royen, MD, Saif Badran, MD, Jorge I. Quintero, MD, MHPE, Tuna Ozyurekoglu, MD
Format: Article
Language:English
Published: Wolters Kluwer 2025-07-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006963
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author Mohammed Muneer, MD
Fadi Bouri, MBBS
Kjell Van Royen, MD
Saif Badran, MD
Jorge I. Quintero, MD, MHPE
Tuna Ozyurekoglu, MD
author_facet Mohammed Muneer, MD
Fadi Bouri, MBBS
Kjell Van Royen, MD
Saif Badran, MD
Jorge I. Quintero, MD, MHPE
Tuna Ozyurekoglu, MD
author_sort Mohammed Muneer, MD
collection DOAJ
description Summary:. Ehlers–Danlos syndrome (EDS) is a group of hereditary disorders that affects collagen synthesis. In the wrist, pain and midcarpal laxity may affect up to 70% of EDS patients. The mainstay treatment of midcarpal instability in patients with ligamentous injury but not EDS includes orthotics, physiotherapy, and activity modification. These methods of conservative treatment may be unsuccessful in controlling instability in the longer term. Using autologous tendon for reconstructing midcarpal instability in patients with EDS carries the risk of loosening over time due to intrinsic abnormalities in collagen metabolism. In this article, we present a novel surgical technique using a cadaveric tendon graft to stabilize bilateral midcarpal instability in EDS patients. A triangular ligament reconstruction from the base of the third metacarpal to the lunate and triquetrum was designed to treat midcarpal instability.
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publisher Wolters Kluwer
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series Plastic and Reconstructive Surgery, Global Open
spelling doaj-art-bc0f630d49e54a44b91b4b533f82fa912025-08-20T03:55:49ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742025-07-01137e696310.1097/GOX.0000000000006963202507000-00036Soft Tissue Stabilization of Midcarpal Instability in Ehlers–Danlos Patients Using a Cadaveric Tendon GraftMohammed Muneer, MD0Fadi Bouri, MBBS1Kjell Van Royen, MD2Saif Badran, MD3Jorge I. Quintero, MD, MHPE4Tuna Ozyurekoglu, MD5From the * Kentucky Hand & Microsurgery Institute, Christine M. Kleinert Institute for Hand and Microsurgery, Louisville, KYFrom the * Kentucky Hand & Microsurgery Institute, Christine M. Kleinert Institute for Hand and Microsurgery, Louisville, KYFrom the * Kentucky Hand & Microsurgery Institute, Christine M. Kleinert Institute for Hand and Microsurgery, Louisville, KY¶ Division of Plastic Surgery, Washington University School of Medicine, St. Louis, MOFrom the * Kentucky Hand & Microsurgery Institute, Christine M. Kleinert Institute for Hand and Microsurgery, Louisville, KYFrom the * Kentucky Hand & Microsurgery Institute, Christine M. Kleinert Institute for Hand and Microsurgery, Louisville, KYSummary:. Ehlers–Danlos syndrome (EDS) is a group of hereditary disorders that affects collagen synthesis. In the wrist, pain and midcarpal laxity may affect up to 70% of EDS patients. The mainstay treatment of midcarpal instability in patients with ligamentous injury but not EDS includes orthotics, physiotherapy, and activity modification. These methods of conservative treatment may be unsuccessful in controlling instability in the longer term. Using autologous tendon for reconstructing midcarpal instability in patients with EDS carries the risk of loosening over time due to intrinsic abnormalities in collagen metabolism. In this article, we present a novel surgical technique using a cadaveric tendon graft to stabilize bilateral midcarpal instability in EDS patients. A triangular ligament reconstruction from the base of the third metacarpal to the lunate and triquetrum was designed to treat midcarpal instability.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006963
spellingShingle Mohammed Muneer, MD
Fadi Bouri, MBBS
Kjell Van Royen, MD
Saif Badran, MD
Jorge I. Quintero, MD, MHPE
Tuna Ozyurekoglu, MD
Soft Tissue Stabilization of Midcarpal Instability in Ehlers–Danlos Patients Using a Cadaveric Tendon Graft
Plastic and Reconstructive Surgery, Global Open
title Soft Tissue Stabilization of Midcarpal Instability in Ehlers–Danlos Patients Using a Cadaveric Tendon Graft
title_full Soft Tissue Stabilization of Midcarpal Instability in Ehlers–Danlos Patients Using a Cadaveric Tendon Graft
title_fullStr Soft Tissue Stabilization of Midcarpal Instability in Ehlers–Danlos Patients Using a Cadaveric Tendon Graft
title_full_unstemmed Soft Tissue Stabilization of Midcarpal Instability in Ehlers–Danlos Patients Using a Cadaveric Tendon Graft
title_short Soft Tissue Stabilization of Midcarpal Instability in Ehlers–Danlos Patients Using a Cadaveric Tendon Graft
title_sort soft tissue stabilization of midcarpal instability in ehlers danlos patients using a cadaveric tendon graft
url http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006963
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