Predictive Factors and Risk Assessment for Hospitalization in Chest Pain Patients Admitted to the Emergency Department

Background: Chest pain is one of the most common reasons for emergency department (ED) visits. Patients presenting with inconclusive symptoms complicate the diagnostic process and add to the burden upon the ED. This study aimed to determine factors possibly influencing ED decisions on hospitalizatio...

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Main Authors: Nadya Kagansky, David Mazor, Ayashi Wajdi, Yulia Maler Yaron, Miya Sharfman, Tomer Ziv Baran, Dana Kagansky, Gal Pachys, Yochai Levy, Daniel Trotzky
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/14/23/2733
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author Nadya Kagansky
David Mazor
Ayashi Wajdi
Yulia Maler Yaron
Miya Sharfman
Tomer Ziv Baran
Dana Kagansky
Gal Pachys
Yochai Levy
Daniel Trotzky
author_facet Nadya Kagansky
David Mazor
Ayashi Wajdi
Yulia Maler Yaron
Miya Sharfman
Tomer Ziv Baran
Dana Kagansky
Gal Pachys
Yochai Levy
Daniel Trotzky
author_sort Nadya Kagansky
collection DOAJ
description Background: Chest pain is one of the most common reasons for emergency department (ED) visits. Patients presenting with inconclusive symptoms complicate the diagnostic process and add to the burden upon the ED. This study aimed to determine factors possibly influencing ED decisions on hospitalization versus discharge for patients with the diagnosis of chest pain. Methods: In the cohort study including 400 patients admitted to the emergency unit with a working diagnosis of chest pain, data on demographics, medical history, symptoms, lab results, and risk scores were collected from the medical records of patients admitted to the ED with a working diagnosis of chest pain. To reduce potential bias, the analysis was restricted to 330 patients who were referred to the ED by a primary care provider or clinic for chest pain. Results: Of 330 patients admitted to the ED, 58.5% were discharged, and 41.5% were hospitalized. Hospitalized patients were significantly older, with a median age of 70 versus 57 years for those discharged (<i>p</i> < 0.001). A higher proportion of hospitalizations occurred during the late-night shift. Significant predictors of hospitalization included hyperlipidemia (OR 3.246), diaphoresis (OR 8.525), dyspnea (OR 2.897), and hypertension (OR 1.959). Nursing home residents had a lower risk of hospitalization (OR 0.381). The area under the ROC curve for this model was 0.801 (95% CI: 0.753–0.848), indicating the predictive accuracy of the model in estimating the probability of admission. The HEART (history, ECG, age, risk factors, and troponin level) score was more effective than the TIMI (Thrombolysis in Myocardial Infarction) score in predicting the need for hospitalization, with an area under the curve (AUC) of 0.807 compared to 0.742 for TIMI. Conclusions: The HEART score in comparison with TIMI score proved especially valuable for quick risk assessment for hospitalization. The model that included hyperlipidemia, diaphoresis, dyspnea, and hypertension was the most predictive for the risk of hospitalization. Further research with larger populations is needed to validate these findings.
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spelling doaj-art-bc05ba776bf44a40b9e4c7c18a0bef0d2024-12-13T16:24:50ZengMDPI AGDiagnostics2075-44182024-12-011423273310.3390/diagnostics14232733Predictive Factors and Risk Assessment for Hospitalization in Chest Pain Patients Admitted to the Emergency DepartmentNadya Kagansky0David Mazor1Ayashi Wajdi2Yulia Maler Yaron3Miya Sharfman4Tomer Ziv Baran5Dana Kagansky6Gal Pachys7Yochai Levy8Daniel Trotzky9Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelShmuel Harofeh Geriatric Medical Center, Be’er Ya’akov 7033001, IsraelSchool of Public Health, Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv 6997801, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelBackground: Chest pain is one of the most common reasons for emergency department (ED) visits. Patients presenting with inconclusive symptoms complicate the diagnostic process and add to the burden upon the ED. This study aimed to determine factors possibly influencing ED decisions on hospitalization versus discharge for patients with the diagnosis of chest pain. Methods: In the cohort study including 400 patients admitted to the emergency unit with a working diagnosis of chest pain, data on demographics, medical history, symptoms, lab results, and risk scores were collected from the medical records of patients admitted to the ED with a working diagnosis of chest pain. To reduce potential bias, the analysis was restricted to 330 patients who were referred to the ED by a primary care provider or clinic for chest pain. Results: Of 330 patients admitted to the ED, 58.5% were discharged, and 41.5% were hospitalized. Hospitalized patients were significantly older, with a median age of 70 versus 57 years for those discharged (<i>p</i> < 0.001). A higher proportion of hospitalizations occurred during the late-night shift. Significant predictors of hospitalization included hyperlipidemia (OR 3.246), diaphoresis (OR 8.525), dyspnea (OR 2.897), and hypertension (OR 1.959). Nursing home residents had a lower risk of hospitalization (OR 0.381). The area under the ROC curve for this model was 0.801 (95% CI: 0.753–0.848), indicating the predictive accuracy of the model in estimating the probability of admission. The HEART (history, ECG, age, risk factors, and troponin level) score was more effective than the TIMI (Thrombolysis in Myocardial Infarction) score in predicting the need for hospitalization, with an area under the curve (AUC) of 0.807 compared to 0.742 for TIMI. Conclusions: The HEART score in comparison with TIMI score proved especially valuable for quick risk assessment for hospitalization. The model that included hyperlipidemia, diaphoresis, dyspnea, and hypertension was the most predictive for the risk of hospitalization. Further research with larger populations is needed to validate these findings.https://www.mdpi.com/2075-4418/14/23/2733chest painemergency departmentacute coronary syndromehospitalizationrisk stratification
spellingShingle Nadya Kagansky
David Mazor
Ayashi Wajdi
Yulia Maler Yaron
Miya Sharfman
Tomer Ziv Baran
Dana Kagansky
Gal Pachys
Yochai Levy
Daniel Trotzky
Predictive Factors and Risk Assessment for Hospitalization in Chest Pain Patients Admitted to the Emergency Department
Diagnostics
chest pain
emergency department
acute coronary syndrome
hospitalization
risk stratification
title Predictive Factors and Risk Assessment for Hospitalization in Chest Pain Patients Admitted to the Emergency Department
title_full Predictive Factors and Risk Assessment for Hospitalization in Chest Pain Patients Admitted to the Emergency Department
title_fullStr Predictive Factors and Risk Assessment for Hospitalization in Chest Pain Patients Admitted to the Emergency Department
title_full_unstemmed Predictive Factors and Risk Assessment for Hospitalization in Chest Pain Patients Admitted to the Emergency Department
title_short Predictive Factors and Risk Assessment for Hospitalization in Chest Pain Patients Admitted to the Emergency Department
title_sort predictive factors and risk assessment for hospitalization in chest pain patients admitted to the emergency department
topic chest pain
emergency department
acute coronary syndrome
hospitalization
risk stratification
url https://www.mdpi.com/2075-4418/14/23/2733
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