TAp73 and ΔTAp73 isoforms show cell-type specific distributions and alterations in cancer
Abstract TP73 is a member of the TP53 gene family and produces N- and C-terminal protein isoforms through alternative promoters, alternative translation initiation and alternative splicing. Most notably, p73 protein isoforms may either contain a p53-like transactivation domain (TAp73 isoforms) or la...
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| Main Authors: | Vaclav Hrabal, Michaela Stenckova, Filip Zavadil Kokas, Petr Muller, Rudolf Nenutil, Borivoj Vojtesek, Philip J. Coates |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-12-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-80927-9 |
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