PRMT5 Inhibitor EPZ015666 Decreases the Viability and Encystment of <i>Entamoeba invadens</i>

PRMT5 Inhibitor EPZ015666 Decreases the Viability and Encystment of <i>Entamoeba invadens</i>

Protein arginine methyltransferase 5 (PRMT5) is an enzyme that produces monomethyl arginine (MMA) and symmetric dimethyl arginine (sDMA), post-translational modifications that regulate several cellular processes, including stage conversion in parasitic protozoans. <i>Entamoeba histolytica</...

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Main Authors: Rigoberto Ortiz-Hernández, Elmer Joel Millán-Casarrubias, Jeni Bolaños, Susana Munguía-Robledo, Carlos Vázquez-Calzada, Elisa Azuara-Licéaga, Jesús Valdés, Mario Alberto Rodríguez
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
<i>Entamoeba invadens</i>
encystment
symmetric arginine dimethylation
PRMT5
Online Access:https://www.mdpi.com/1420-3049/30/1/62
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