First Incidence of Peste des Petits Ruminants Virus in <i>Cervidae</i> Family from State Zoo of Assam, India
The present study aimed to investigate the episodes of per-acute mortality due to peste des petits ruminants (PPR) that resulted in the death of 30 animals of different species of cervids, namely, barking deer, four-horned antelope, hog deer, thamin, and mouse deer in the State Zoo of Assam, a north...
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2024-11-01
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| author | Nagendra Nath Barman Arpita Bharali Durlav Prasad Bora Biswajit Dutta Mousumi Bora Sophia M. Gogoi Panchami Sharma Sankar Sarma Parikshit Kakati Tejas Mariswamy Ankita Choudhury Lukumoni Buragohain |
| author_facet | Nagendra Nath Barman Arpita Bharali Durlav Prasad Bora Biswajit Dutta Mousumi Bora Sophia M. Gogoi Panchami Sharma Sankar Sarma Parikshit Kakati Tejas Mariswamy Ankita Choudhury Lukumoni Buragohain |
| author_sort | Nagendra Nath Barman |
| collection | DOAJ |
| description | The present study aimed to investigate the episodes of per-acute mortality due to peste des petits ruminants (PPR) that resulted in the death of 30 animals of different species of cervids, namely, barking deer, four-horned antelope, hog deer, thamin, and mouse deer in the State Zoo of Assam, a northeastern state of India. The affected animals showed no to limited clinical signs. However, the necropsy and histopathological findings were highly suggestive of PPR virus (PPRV) infection observed in domestic small ruminants. Representative tissue samples were screened for the presence of PPRV along with blue tongue virus (BTV) and epizootic hemorrhagic disease virus (EHDV) using RT-PCR or RT-qPCR and were found to be positive for PPRV. Considering the sudden outbreak of PPR in captive cervids, we sought to determine the role of domestic goats as the potential spillover host. To verify that, archived tissue samples of domestic goats collected during PPRV outbreaks in nearby localities and slaughtered goats used as meat for Carnivorous animals in the State Zoo were also screened and found to be positive for PPRV in RT-PCR. Phylogenetic analysis based on the Nucleocapsid (N) protein gene of PPRV from infected cervids, domestic goats, and goat meat revealed the virus to be of Lineage IV origin. Our findings provide evidence of probable spillover of PPRV from domestic goats to captive endangered cervids and circulation of Lineage IV PPRV strains among the small-ruminant population of this region. |
| format | Article |
| id | doaj-art-bbb55b0cf80048f59c203e34828a37c2 |
| institution | Kabale University |
| issn | 1999-4915 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj-art-bbb55b0cf80048f59c203e34828a37c22024-12-27T14:58:58ZengMDPI AGViruses1999-49152024-11-011612182910.3390/v16121829First Incidence of Peste des Petits Ruminants Virus in <i>Cervidae</i> Family from State Zoo of Assam, IndiaNagendra Nath Barman0Arpita Bharali1Durlav Prasad Bora2Biswajit Dutta3Mousumi Bora4Sophia M. Gogoi5Panchami Sharma6Sankar Sarma7Parikshit Kakati8Tejas Mariswamy9Ankita Choudhury10Lukumoni Buragohain11College of Veterinary Science, Assam Agricultural University, Guwahati 781022, Assam, IndiaCollege of Veterinary Science, Assam Agricultural University, Guwahati 781022, Assam, IndiaCollege of Veterinary Science, Assam Agricultural University, Guwahati 781022, Assam, IndiaCollege of Veterinary Science, Assam Agricultural University, Guwahati 781022, Assam, IndiaCollege of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana 141004, Punjab, IndiaCollege of Veterinary Science, Assam Agricultural University, Guwahati 781022, Assam, IndiaAssam State Zoo-cum-Botanical Garden, Guwahati 781005, Assam, IndiaAssam State Zoo-cum-Botanical Garden, Guwahati 781005, Assam, IndiaWorld Wildlife Fund (WWF-India), Guwahati 781029, Assam, IndiaAssam State Zoo-cum-Botanical Garden, Guwahati 781005, Assam, IndiaCollege of Veterinary Science, Assam Agricultural University, Guwahati 781022, Assam, IndiaCollege of Veterinary Science, Assam Agricultural University, Guwahati 781022, Assam, IndiaThe present study aimed to investigate the episodes of per-acute mortality due to peste des petits ruminants (PPR) that resulted in the death of 30 animals of different species of cervids, namely, barking deer, four-horned antelope, hog deer, thamin, and mouse deer in the State Zoo of Assam, a northeastern state of India. The affected animals showed no to limited clinical signs. However, the necropsy and histopathological findings were highly suggestive of PPR virus (PPRV) infection observed in domestic small ruminants. Representative tissue samples were screened for the presence of PPRV along with blue tongue virus (BTV) and epizootic hemorrhagic disease virus (EHDV) using RT-PCR or RT-qPCR and were found to be positive for PPRV. Considering the sudden outbreak of PPR in captive cervids, we sought to determine the role of domestic goats as the potential spillover host. To verify that, archived tissue samples of domestic goats collected during PPRV outbreaks in nearby localities and slaughtered goats used as meat for Carnivorous animals in the State Zoo were also screened and found to be positive for PPRV in RT-PCR. Phylogenetic analysis based on the Nucleocapsid (N) protein gene of PPRV from infected cervids, domestic goats, and goat meat revealed the virus to be of Lineage IV origin. Our findings provide evidence of probable spillover of PPRV from domestic goats to captive endangered cervids and circulation of Lineage IV PPRV strains among the small-ruminant population of this region.https://www.mdpi.com/1999-4915/16/12/1829Assam State Zoocervidslineage IVpeste des petits ruminants virusspillover |
| spellingShingle | Nagendra Nath Barman Arpita Bharali Durlav Prasad Bora Biswajit Dutta Mousumi Bora Sophia M. Gogoi Panchami Sharma Sankar Sarma Parikshit Kakati Tejas Mariswamy Ankita Choudhury Lukumoni Buragohain First Incidence of Peste des Petits Ruminants Virus in <i>Cervidae</i> Family from State Zoo of Assam, India Viruses Assam State Zoo cervids lineage IV peste des petits ruminants virus spillover |
| title | First Incidence of Peste des Petits Ruminants Virus in <i>Cervidae</i> Family from State Zoo of Assam, India |
| title_full | First Incidence of Peste des Petits Ruminants Virus in <i>Cervidae</i> Family from State Zoo of Assam, India |
| title_fullStr | First Incidence of Peste des Petits Ruminants Virus in <i>Cervidae</i> Family from State Zoo of Assam, India |
| title_full_unstemmed | First Incidence of Peste des Petits Ruminants Virus in <i>Cervidae</i> Family from State Zoo of Assam, India |
| title_short | First Incidence of Peste des Petits Ruminants Virus in <i>Cervidae</i> Family from State Zoo of Assam, India |
| title_sort | first incidence of peste des petits ruminants virus in i cervidae i family from state zoo of assam india |
| topic | Assam State Zoo cervids lineage IV peste des petits ruminants virus spillover |
| url | https://www.mdpi.com/1999-4915/16/12/1829 |
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