Aldehyde Dehydrogenase 2 Ameliorates LPS-Induced Acute Kidney Injury through Detoxification of 4-HNE and Suppression of the MAPK Pathway

Aldehyde Dehydrogenase 2 Ameliorates LPS-Induced Acute Kidney Injury through Detoxification of 4-HNE and Suppression of the MAPK Pathway

Lipopolysaccharide (LPS)-induced septic acute kidney injury (AKI) is determined as a devastating organ dysfunction elicited by an inappropriate response to infection with high morbidity and mortality rates. Previous evidence has illustrated an indispensable role of mitochondrial aldehyde dehydrogena...

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Bibliographic Details
Main Authors:	Jifu Jin, Rebecca Suchi Chang, Sujuan Xu, Guang Xia, Jennifer Ming Jen Wong, Yi Fang, Ping Jia, Xiaoqiang Ding
Format:	Article
Language:	English
Published:	Wiley 2023-01-01
Series:	Journal of Immunology Research
Online Access:	http://dx.doi.org/10.1155/2023/5513507
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