Flow-cytometry reveals mitochondrial DNA accumulation in Saccharomyces cerevisiae cells during cell cycle arrest

Flow-cytometry reveals mitochondrial DNA accumulation in Saccharomyces cerevisiae cells during cell cycle arrest

Mitochondria are semi-autonomous organelles containing their own DNA (mtDNA), which is replicated independently of nuclear DNA (nDNA). While cell cycle arrest halts nDNA replication, mtDNA replication continues. In Saccharomyces cerevisiae, flow cytometry enables semi-quantitative estimation of mtDN...

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Bibliographic Details
Main Authors:	Elena Yu Potapenko, Nataliia D. Kashko, Dmitry A. Knorre
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-12-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	mtDNA yeast mtDNA copy number control mtDNA copy number cell cycle arrest cell cycle defect
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1497652/full
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