Assessment of the Presence of Free-Living Amoebae in Soil Samples from the Northwest Region of Spain Using Culture and Molecular Assays

Free-living amoebae (FLA) such as <i>Acanthamoeba</i> spp., <i>Balamuthia mandrillaris</i>, <i>Naegleria fowleri</i>, <i>Sappinia</i> spp., <i>Vahlkampfia</i> spp., and <i>Vermamoeba vermiformis</i> are naturally widespread in t...

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Main Authors: Patricia Pérez-Pérez, Iván Rodríguez-Escolar, Elizabeth Córdoba-Lanús, Angélica Domínguez-de-Barros, Omar García-Pérez, José E. Piñero, Rodrigo Morchón, Jacob Lorenzo-Morales
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/13/5/1065
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Summary:Free-living amoebae (FLA) such as <i>Acanthamoeba</i> spp., <i>Balamuthia mandrillaris</i>, <i>Naegleria fowleri</i>, <i>Sappinia</i> spp., <i>Vahlkampfia</i> spp., and <i>Vermamoeba vermiformis</i> are naturally widespread in the environment, causing rare but fatal and debilitating infections in humans. In the present study, a total of 87 soil samples were collected from four provinces in the autonomous community of Castilla y León, Spain. These samples were collected in three different seasons during 2022–2023 (t1–t3) and were analysed by culture and molecular techniques (conventional PCR/sanger sequencing and qPCR). The obtained data revealed that the genus <i>Acanthamoeba</i> and the species <i>Vermamoeba vermiformis</i> were the most prevalent FLA. Furthermore, other genera/species of FLA were identified in the tested soil sources, suggesting a rich microbial biodiversity in Castilla y León soils. In addition, this study provides an important basis for future research on the ecology of these organisms and their potential impact on public health and the environment.
ISSN:2076-2607