Gaining insights into the physicochemical properties and sequence space of blood–brain barrier penetrating peptides

Gaining insights into the physicochemical properties and sequence space of blood–brain barrier penetrating peptides

The blood–brain barrier (BBB) poses a significant obstacle to the administration of drugs to the brain for the development of therapies of central nervous system (CNS) disorders. Blood-brain barrier penetrating peptides (BBBPps) are a group of peptides that can traverse the BBB by different processe...

Full description

Saved in:

Bibliographic Details
Main Authors:	Abhigyan Nath, Sneha Pandey, Kottakkaran Sooppy Nisar, Anoop Kumar Tiwari
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Series:	Egyptian Informatics Journal
Subjects:	Blood brain barrier penetrating peptides Sequence properties Physicochemical space Gradient boosting machines XGboost Model agnostic interpretation methods
Online Access:	http://www.sciencedirect.com/science/article/pii/S1110866524001208
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Advances and prospects of cell-penetrating peptides in tumor immunotherapy
by: Di Yang, et al.
Published: (2025-01-01)

Tumor-Targeted Cell-Penetrating Peptides Reveal That Monomethyl Auristatin E Temporally Modulates the Tumor Immune Microenvironment
by: Mahsa Mortaja, et al.
Published: (2024-11-01)

Guanidines Conjugated with Cell-Penetrating Peptides: A New Approach for the Development of Antileishmanial Molecules
by: João Victor Marcelino de Souza, et al.
Published: (2025-01-01)

New Conjugates of Vancomycin with Cell-Penetrating Peptides—Synthesis, Antimicrobial Activity, Cytotoxicity, and BBB Permeability Studies
by: Jarosław Ruczyński, et al.
Published: (2024-11-01)

Applications of cell penetrating peptide-based drug delivery system in immunotherapy
by: Jing-Jing Du, et al.
Published: (2025-01-01)

A cell-penetrating bispecific antibody suppresses hepatitis B virus replication and secretion
by: Chongwei Xie, et al.
Published: (2025-03-01)

Leveraging machine learning to predict residential location choice: A comparative analysis
by: Vahid Noferesti, et al.
Published: (2025-03-01)

Modeling Ionospheric TEC Using Gradient Boosting Based and Stacking Machine Learning Techniques
by: Ayanew Nigusie, et al.
Published: (2024-03-01)

In vitro and ex vivo screening of microRNA combinations with enhanced cell penetrating peptides to stimulate intervertebral disc regeneration
by: Tara Ní Néill, et al.
Published: (2024-12-01)

Thou shalt not pass - arachnid venom peptides interacting with biological membranes
by: Yachen Wang, et al.
Published: (2024-11-01)

Molecular aspects of cell-penetrating peptides: key amino acids, membrane partners, and non-covalent interactions
by: Walrant, Astrid, et al.
Published: (2025-01-01)

A meta-learning based stacked regression approach for customer lifetime value prediction
by: Karan Gadgil, et al.
Published: (2023-11-01)

Explainable Model Prediction of Memristor
by: Sruthi Pallathuvalappil, et al.
Published: (2024-01-01)

Advanced techniques for wind energy production forecasting: Leveraging multi-layer Perceptron + Bayesian optimization, ensemble learning, and CNN-LSTM models
by: Seyed Matin Malakouti, et al.
Published: (2024-12-01)

A bird’s-eye view of the biological mechanism and machine learning prediction approaches for cell-penetrating peptides
by: Maduravani Ramasundaram, et al.
Published: (2025-01-01)

Relevant SMS Spam Feature Selection Using Wrapper Approach and XGBoost Algorithm
by: Diyari Jalal Mussa, et al.
Published: (2019-11-01)

Dietary Influence on Growth, Physicochemical Stability, and Antimicrobial Mechanisms of Antimicrobial Peptides in Black Soldier Fly Larvae
by: Shaojuan Liu, et al.
Published: (2024-11-01)

Early identification of dropouts during the special forces selection program
by: Ruud J. R. den Hartigh, et al.
Published: (2025-01-01)

Development of a cell-penetrating peptide-based nanocomplex for long-term delivery of intact mitochondrial DNA into epithelial cells
by: Kyrie Wilson, et al.
Published: (2025-03-01)

Evaluating the impact of cell-penetrating motif position on the cellular uptake of magnetite nanoparticles
by: Laura Salgado, et al.
Published: (2024-12-01)

Enhancing DNA Vaccine Delivery Through Stearyl-Modified Cell-Penetrating Peptides: Improved Antigen Expression and Immune Response In Vitro and In Vivo
by: Sheng Jiang, et al.
Published: (2025-01-01)

An efficient computational investigation on accurate daily soil temperature prediction using boosting ensemble methods explanation based on SHAP importance analysis
by: Meysam Alizamir, et al.
Published: (2024-12-01)

Online Prediction and Correction of Static Voltage Stability Index Based on Extreme Gradient Boosting Algorithm
by: Huiling Qin, et al.
Published: (2024-11-01)

A Perspective on Explainable Artificial Intelligence Methods: SHAP and LIME
by: Ahmed M. Salih, et al.
Published: (2025-01-01)

Prediction of High-Pressure Physical Properties of Crude Oil Using Explainable Machine Learning Models
by: Yawen He, et al.
Published: (2025-01-01)

Forestry climate adaptation with HarvesterSeasons service—a gradient boosting model to forecast soil water index SWI from a comprehensive set of predictors in Destination Earth
by: Mikko Strahlendorff, et al.
Published: (2024-12-01)

Research on Fault Diagnosis Method for Photovoltaic Array Based on XGBoost Algorithm
by: Zongyu Zhang, et al.
Published: (2024-11-01)

Fusion Partner Facilitates Expression of Cell-Penetrating Peptide L2 in <i>Pichia pastoris</i>
by: Xuan Li, et al.
Published: (2024-12-01)

Identifying the Roadway Infrastructure Factors Affecting Road Accidents Using Interpretable Machine Learning and Data Augmentation
by: Jonghak Lee, et al.
Published: (2025-01-01)

Audio analysis with convolutional neural networks and boosting algorithms tuned by metaheuristics for respiratory condition classification
by: Safet Purkovic, et al.
Published: (2024-12-01)

Identification and susceptibility assessment of landslide disasters in the red bed formation along the Nanjian-Jingdong Expressway
by: Yifan Cao, et al.
Published: (2025-01-01)

Robust diabetic prediction using ensemble machine learning models with synthetic minority over-sampling technique
by: Pradeepa Sampath, et al.
Published: (2024-11-01)

Efficient diagnosis of diabetes mellitus using an improved ensemble method
by: Blessing Oluwatobi Olorunfemi, et al.
Published: (2025-01-01)

A computational approach for prediction of viscosity of chemical compounds based on molecular structures
by: Sneha Das, et al.
Published: (2025-01-01)

Feature selection enhances peptide binding predictions for TCR-specific interactions
by: Hamid Teimouri, et al.
Published: (2025-01-01)

Short-term photovoltaic power prediction combination model considering seasonal characteristic and data window
by: ZHANG Jing, et al.
Published: (2025-01-01)

A novel light GBM framework combined with gain optimization for predicting dementia severity of Alzheimer’s disease
by: R. Roopalakshmi, et al.
Published: (2024-12-01)

Machine Learning-Driven Resilient Modulus Prediction for Flexible Pavements Across Mountainous and Other Regions
by: Rauf Ayesha, et al.
Published: (2025-01-01)

Reagent-free Hyperspectral Diagnosis of SARS-CoV-2 Infection in Saliva Samples
by: Brandon Saint-John, et al.
Published: (2025-01-01)

High-velocity projectile penetration test and theoretical calculation of pseudo fluid penetration of calcareous sand
by: Wei Guo, et al.
Published: (2024-12-01)