Boronic Acid-Containing 3<i>H</i>- pyrazolo[4,3-<i>f</i>]quinoline Compounds as Dual CLK/ROCK Inhibitors with Anticancer Properties

<b>Background:</b> The protein kinases CLK and ROCK play key roles in cell growth and migration, respectively, and are potential anticancer targets. ROCK inhibitors have been approved by the FDA for various diseases and CLK inhibitors are currently being trialed in the clinic as anticanc...

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Bibliographic Details
Main Authors: Neetu Dayal, Riddhi Chaudhuri, Kofi Simpa Yeboah, Nickolas R. Brauer, Herman O. Sintim
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceuticals
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Online Access:https://www.mdpi.com/1424-8247/17/12/1660
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