Tppp3 is a novel molecule for retinal ganglion cell identification and optic nerve regeneration

Tppp3 is a novel molecule for retinal ganglion cell identification and optic nerve regeneration

Abstract Mammalian central nervous system (CNS) axons cannot spontaneously regenerate after injury, creating an unmet need to identify molecular regulators to promote axon regeneration and reduce the lasting impact of CNS injuries. While tubulin polymerization promoting protein family member 3 (Tppp...

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Bibliographic Details
Main Authors: Mishal Rao, Ziming Luo, Chia-Chun Liu, Chi-Yu Chen, Shining Wang, Michael Nahmou, Bogdan Tanasa, Aman Virmani, Leah Byrne, Jeffrey L. Goldberg, José-Alain Sahel, Kun-Che Chang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Acta Neuropathologica Communications
Subjects:
Tppp3
Retinal ganglion cells
Axon regeneration
Neurite outgrowth
BMP4
Inflammation
Online Access:https://doi.org/10.1186/s40478-024-01917-6
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