Integrated model for segmentation of glomeruli in kidney images

Kidney diseases, especially those that affect the glomeruli, have become more common worldwide in recent years. Accurate and early detection of glomeruli is critical for accurately diagnosing kidney problems and determining the most effective treatment options. Our study proposed an advanced model,...

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Main Authors: Gurjinder Kaur, Meenu Garg, Sheifali Gupta
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2025-01-01
Series:Cognitive Robotics
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667241324000211
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author Gurjinder Kaur
Meenu Garg
Sheifali Gupta
author_facet Gurjinder Kaur
Meenu Garg
Sheifali Gupta
author_sort Gurjinder Kaur
collection DOAJ
description Kidney diseases, especially those that affect the glomeruli, have become more common worldwide in recent years. Accurate and early detection of glomeruli is critical for accurately diagnosing kidney problems and determining the most effective treatment options. Our study proposed an advanced model, FResMRCNN, an enhanced version of Mask R-CNN, for automatically detecting and segmenting the glomeruli in PAS-stained human kidney images. The model integrates the power of FPN with a ResNet101 backbone, which was selected after assessing seven different backbone architectures. The integration of FPN and ResNet101 into the FResMRCNN model improves glomeruli detection, segmentation accuracy and stability by representing multi-scale features. We trained and tested our model using the HuBMAP Kidney dataset, which contains high-resolution PAS-stained microscopy images. During the study, the effectiveness of our proposed model is examined by generating bounding boxes and predicted masks of glomeruli. The performance of the FResMRCNN model is evaluated using three performance metrics, including the Dice coefficient, Jaccard index, and binary cross-entropy loss, which show promising results in accurately segmenting glomeruli.
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spelling doaj-art-ba86cdc320b34a55a7da37bd0900f17f2024-12-13T11:07:12ZengKeAi Communications Co. Ltd.Cognitive Robotics2667-24132025-01-015113Integrated model for segmentation of glomeruli in kidney imagesGurjinder Kaur0Meenu Garg1Sheifali Gupta2Corresponding author.; Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, Punjab, IndiaChitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, Punjab, IndiaChitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, Punjab, IndiaKidney diseases, especially those that affect the glomeruli, have become more common worldwide in recent years. Accurate and early detection of glomeruli is critical for accurately diagnosing kidney problems and determining the most effective treatment options. Our study proposed an advanced model, FResMRCNN, an enhanced version of Mask R-CNN, for automatically detecting and segmenting the glomeruli in PAS-stained human kidney images. The model integrates the power of FPN with a ResNet101 backbone, which was selected after assessing seven different backbone architectures. The integration of FPN and ResNet101 into the FResMRCNN model improves glomeruli detection, segmentation accuracy and stability by representing multi-scale features. We trained and tested our model using the HuBMAP Kidney dataset, which contains high-resolution PAS-stained microscopy images. During the study, the effectiveness of our proposed model is examined by generating bounding boxes and predicted masks of glomeruli. The performance of the FResMRCNN model is evaluated using three performance metrics, including the Dice coefficient, Jaccard index, and binary cross-entropy loss, which show promising results in accurately segmenting glomeruli.http://www.sciencedirect.com/science/article/pii/S2667241324000211GlomeruliSegmentationFResMRCNNResNet101HuBMAP datasetKidney
spellingShingle Gurjinder Kaur
Meenu Garg
Sheifali Gupta
Integrated model for segmentation of glomeruli in kidney images
Cognitive Robotics
Glomeruli
Segmentation
FResMRCNN
ResNet101
HuBMAP dataset
Kidney
title Integrated model for segmentation of glomeruli in kidney images
title_full Integrated model for segmentation of glomeruli in kidney images
title_fullStr Integrated model for segmentation of glomeruli in kidney images
title_full_unstemmed Integrated model for segmentation of glomeruli in kidney images
title_short Integrated model for segmentation of glomeruli in kidney images
title_sort integrated model for segmentation of glomeruli in kidney images
topic Glomeruli
Segmentation
FResMRCNN
ResNet101
HuBMAP dataset
Kidney
url http://www.sciencedirect.com/science/article/pii/S2667241324000211
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