Identification of CDKN3 overexpression as a marker of poor prognosis and potential therapeutic target in low-grade glioma

Identification of CDKN3 overexpression as a marker of poor prognosis and potential therapeutic target in low-grade glioma

Abstract Low-grade glioma (LGG) is a primary, slow-growing brain tumor; however, its treatment and prognosis remain challenging. In this study, we analyzed cancer data from the TCGA database, focusing particularly on the expression of the CDKN3 gene in LGG. The results showed that high CDKN3 express...

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Bibliographic Details
Main Authors: Hongbing Cheng, Xiao Meng, Yanhua Zhang, Pu Wang, Yucheng Lu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Low-grade glioma
CDKN3
Prognosis
Immune infiltration
Online Access:https://doi.org/10.1038/s41598-025-86338-8
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