Antimicrobial Effectiveness of Endodontic Irrigants Against E. Faecalis: An In vitro Study
Aim: This in vitro study compared the antimicrobial efficacy of 5.25% sodium hypochlorite, 10% citric acid, and 3% hydrogen peroxide against Enterococcus faecalis (E. faecalis), using normal saline as a control. Method: E. faecalis isolates were exposed to different irrigants, with bacterial colony...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
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| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_475_24 |
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| author | Ajay Chhabra B. Saravana Prathap KP Ramya Priyanka Yadav Himani Mehra Sona J. Parvathy Gayatree Nayak |
| author_facet | Ajay Chhabra B. Saravana Prathap KP Ramya Priyanka Yadav Himani Mehra Sona J. Parvathy Gayatree Nayak |
| author_sort | Ajay Chhabra |
| collection | DOAJ |
| description | Aim:
This in vitro study compared the antimicrobial efficacy of 5.25% sodium hypochlorite, 10% citric acid, and 3% hydrogen peroxide against Enterococcus faecalis (E. faecalis), using normal saline as a control.
Method:
E. faecalis isolates were exposed to different irrigants, with bacterial colony counts measured at various intervals using the spread plate method.
Results:
Sodium hypochlorite and citric acid effectively inhibited E. faecalis, while hydrogen peroxide was less effective. Sodium hypochlorite dissolved tissues and acted germicidally; citric acid disrupted bacterial structures through low pH. Hydrogen peroxide’s effect was due to free radical formation and oxygen release.
Conclusion:
Both 5.25% sodium hypochlorite and 10% citric acid showed equal efficacy against E. faecalis, while hydrogen peroxide was less effective. Further research should explore clinical applications and polymicrobial biofilms. |
| format | Article |
| id | doaj-art-ba68495c56fe4051b0efccb258d5155d |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-ba68495c56fe4051b0efccb258d5155d2025-01-12T14:05:31ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3120S312310.4103/jpbs.jpbs_475_24Antimicrobial Effectiveness of Endodontic Irrigants Against E. Faecalis: An In vitro StudyAjay ChhabraB. Saravana PrathapKP RamyaPriyanka YadavHimani MehraSona J. ParvathyGayatree NayakAim: This in vitro study compared the antimicrobial efficacy of 5.25% sodium hypochlorite, 10% citric acid, and 3% hydrogen peroxide against Enterococcus faecalis (E. faecalis), using normal saline as a control. Method: E. faecalis isolates were exposed to different irrigants, with bacterial colony counts measured at various intervals using the spread plate method. Results: Sodium hypochlorite and citric acid effectively inhibited E. faecalis, while hydrogen peroxide was less effective. Sodium hypochlorite dissolved tissues and acted germicidally; citric acid disrupted bacterial structures through low pH. Hydrogen peroxide’s effect was due to free radical formation and oxygen release. Conclusion: Both 5.25% sodium hypochlorite and 10% citric acid showed equal efficacy against E. faecalis, while hydrogen peroxide was less effective. Further research should explore clinical applications and polymicrobial biofilms.https://journals.lww.com/10.4103/jpbs.jpbs_475_24antimicrobial efficacycitric acidendodontic irrigantsenterococcus faecalishydrogen peroxidesodium hypochlorite |
| spellingShingle | Ajay Chhabra B. Saravana Prathap KP Ramya Priyanka Yadav Himani Mehra Sona J. Parvathy Gayatree Nayak Antimicrobial Effectiveness of Endodontic Irrigants Against E. Faecalis: An In vitro Study Journal of Pharmacy and Bioallied Sciences antimicrobial efficacy citric acid endodontic irrigants enterococcus faecalis hydrogen peroxide sodium hypochlorite |
| title | Antimicrobial Effectiveness of Endodontic Irrigants Against E. Faecalis: An In vitro Study |
| title_full | Antimicrobial Effectiveness of Endodontic Irrigants Against E. Faecalis: An In vitro Study |
| title_fullStr | Antimicrobial Effectiveness of Endodontic Irrigants Against E. Faecalis: An In vitro Study |
| title_full_unstemmed | Antimicrobial Effectiveness of Endodontic Irrigants Against E. Faecalis: An In vitro Study |
| title_short | Antimicrobial Effectiveness of Endodontic Irrigants Against E. Faecalis: An In vitro Study |
| title_sort | antimicrobial effectiveness of endodontic irrigants against e faecalis an in vitro study |
| topic | antimicrobial efficacy citric acid endodontic irrigants enterococcus faecalis hydrogen peroxide sodium hypochlorite |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_475_24 |
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