Antimicrobial Effectiveness of Endodontic Irrigants Against E. Faecalis: An In vitro Study
Aim: This in vitro study compared the antimicrobial efficacy of 5.25% sodium hypochlorite, 10% citric acid, and 3% hydrogen peroxide against Enterococcus faecalis (E. faecalis), using normal saline as a control. Method: E. faecalis isolates were exposed to different irrigants, with bacterial colony...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_475_24 |
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| Summary: | Aim:
This in vitro study compared the antimicrobial efficacy of 5.25% sodium hypochlorite, 10% citric acid, and 3% hydrogen peroxide against Enterococcus faecalis (E. faecalis), using normal saline as a control.
Method:
E. faecalis isolates were exposed to different irrigants, with bacterial colony counts measured at various intervals using the spread plate method.
Results:
Sodium hypochlorite and citric acid effectively inhibited E. faecalis, while hydrogen peroxide was less effective. Sodium hypochlorite dissolved tissues and acted germicidally; citric acid disrupted bacterial structures through low pH. Hydrogen peroxide’s effect was due to free radical formation and oxygen release.
Conclusion:
Both 5.25% sodium hypochlorite and 10% citric acid showed equal efficacy against E. faecalis, while hydrogen peroxide was less effective. Further research should explore clinical applications and polymicrobial biofilms. |
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| ISSN: | 0976-4879 0975-7406 |