GRB2, a protein known for a long time with a new autophagy-regulating function

GRB2, a protein known for a long time with a new autophagy-regulating function

BECN1 (BCL2 interacting myosin like coiled protein) is a major regulator of autophagy and a haploinsufficient tumor suppressor. BECN1 binds to multiple proteins and it is part of at least two different class III phosphatidylinositol (PI) 3 Kinase (PI3KC3) complexes that regulate autophagy and endocy...

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Bibliographic Details
Main Author: Silvia Vega-Rubin-de-Celis
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Autophagy Reports
Subjects:
BECN1
GRB2
autophagy
PI3KC3
tumorigenesis
CAM assay
Online Access:https://www.tandfonline.com/doi/10.1080/27694127.2024.2325265
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