Technical Note: Rapid Species Barcoding Using Bento Lab Mobile Laboratory

In scenarios when the morphological identification of samples is not feasible, the utilization of molecular analyses becomes an imperative. However, that can often be challenging in conditions where standard molecular laboratories cannot be established. In this study, we present a simplified and fie...

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Main Authors: Karolina Mahlerová, Lenka Vaňková, Marcin Tomsia, Daniel Vaněk
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Forensic Sciences
Subjects:
Online Access:https://www.mdpi.com/2673-6756/4/4/38
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author Karolina Mahlerová
Lenka Vaňková
Marcin Tomsia
Daniel Vaněk
author_facet Karolina Mahlerová
Lenka Vaňková
Marcin Tomsia
Daniel Vaněk
author_sort Karolina Mahlerová
collection DOAJ
description In scenarios when the morphological identification of samples is not feasible, the utilization of molecular analyses becomes an imperative. However, that can often be challenging in conditions where standard molecular laboratories cannot be established. In this study, we present a simplified and field-friendly protocol of the previously published Triplex PCR Assay for the identification of mammalian and plant sample origin using a fully portable molecular laboratory from Bento Lab (Bento Bioworks Ltd., London, UK), effectively eliminating the need for a traditional laboratory setup. The protocol in combination with correctly selected kits enables DNA extraction, result evaluation based on electrophoresis, and direct use of the PCR products for downstream analyses such as Sanger sequencing and third-generation sequencing; therefore, enabling the use of molecular analysis directly in situ or for educational purposes in a classroom.
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institution Kabale University
issn 2673-6756
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publishDate 2024-10-01
publisher MDPI AG
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series Forensic Sciences
spelling doaj-art-b9fb09c9d2244c8b809cd317d1adbd762024-12-27T14:26:52ZengMDPI AGForensic Sciences2673-67562024-10-014456657210.3390/forensicsci4040038Technical Note: Rapid Species Barcoding Using Bento Lab Mobile LaboratoryKarolina Mahlerová0Lenka Vaňková1Marcin Tomsia2Daniel Vaněk3Institute for Environmental Studies, Charles University Prague, Benátská 2, 128 01 Prague, Czech RepublicInstitute for Environmental Studies, Charles University Prague, Benátská 2, 128 01 Prague, Czech RepublicDepartment of Forensic Medicine and Forensic Toxicology, Faculty of Medical Sciences (FOMS) in Katowice, Medical University of Silesia, 18 Medyków Street, 40-752 Katowice, PolandInstitute for Environmental Studies, Charles University Prague, Benátská 2, 128 01 Prague, Czech RepublicIn scenarios when the morphological identification of samples is not feasible, the utilization of molecular analyses becomes an imperative. However, that can often be challenging in conditions where standard molecular laboratories cannot be established. In this study, we present a simplified and field-friendly protocol of the previously published Triplex PCR Assay for the identification of mammalian and plant sample origin using a fully portable molecular laboratory from Bento Lab (Bento Bioworks Ltd., London, UK), effectively eliminating the need for a traditional laboratory setup. The protocol in combination with correctly selected kits enables DNA extraction, result evaluation based on electrophoresis, and direct use of the PCR products for downstream analyses such as Sanger sequencing and third-generation sequencing; therefore, enabling the use of molecular analysis directly in situ or for educational purposes in a classroom.https://www.mdpi.com/2673-6756/4/4/38Bento Labmobile laboratorybarcodingCOIRuBisCOin situ
spellingShingle Karolina Mahlerová
Lenka Vaňková
Marcin Tomsia
Daniel Vaněk
Technical Note: Rapid Species Barcoding Using Bento Lab Mobile Laboratory
Forensic Sciences
Bento Lab
mobile laboratory
barcoding
COI
RuBisCO
in situ
title Technical Note: Rapid Species Barcoding Using Bento Lab Mobile Laboratory
title_full Technical Note: Rapid Species Barcoding Using Bento Lab Mobile Laboratory
title_fullStr Technical Note: Rapid Species Barcoding Using Bento Lab Mobile Laboratory
title_full_unstemmed Technical Note: Rapid Species Barcoding Using Bento Lab Mobile Laboratory
title_short Technical Note: Rapid Species Barcoding Using Bento Lab Mobile Laboratory
title_sort technical note rapid species barcoding using bento lab mobile laboratory
topic Bento Lab
mobile laboratory
barcoding
COI
RuBisCO
in situ
url https://www.mdpi.com/2673-6756/4/4/38
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AT danielvanek technicalnoterapidspeciesbarcodingusingbentolabmobilelaboratory