Human-Induced Pluripotent Stem Cells (iPSCs) for Disease Modeling and Insulin Target Cell Regeneration in the Treatment of Insulin Resistance: A Review

Human-Induced Pluripotent Stem Cells (iPSCs) for Disease Modeling and Insulin Target Cell Regeneration in the Treatment of Insulin Resistance: A Review

Diabetes mellitus, both type 1 (T1D) and type 2 (T2D), has become the epidemic of the century and a major public health concern given its rising prevalence and the increasing adoption of a sedentary lifestyle globally. This multifaceted disease is characterized by impaired pancreatic beta cell funct...

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Bibliographic Details
Main Authors: Sama Thiab, Juberiya M. Azeez, Alekya Anala, Moksha Nanda, Somieya Khan, Alexandra E. Butler, Manjula Nandakumar
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Series:Cells
Subjects:
human-induced pluripotent stem cells
insulin resistance
diabetes mellitus
iPSC-derived insulin target cells
iPSC differentiation
Online Access:https://www.mdpi.com/2073-4409/14/15/1188
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