Renal impairment as a risk factor for chemotherapy induced neutropenia in the treatment of trifluridine/thymidine phosphorylase inhibitor plus bevacizumab
Abstract Although the phase III SUNLIGHT trial has demonstrated the survival benefit of the addition of bevacizumab (Bmab) to trifluridine/thymidine phosphorylase inhibitor (FTD/TPI), neutropenia, which frequently occurs during FDT/TPI + Bmab therapy, is a concern for clinicians. As TPI is excreted...
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Main Authors: | Masatsune Shibutani, Hideki Tanda, Hiroaki Kasashima, Tatsunari Fukuoka, Shinichiro Kashiwagi, Kiyoshi Maeda |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Scientific Reports |
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Online Access: | https://doi.org/10.1038/s41598-024-84133-5 |
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