Effect of Global ATGL Knockout on Murine Fasting Glucose Kinetics
Mice deficient in adipose triglyceride lipase (ATGL−/−) present elevated ectopic lipid levels but are paradoxically glucose-tolerant. Measurement of endogenous glucose production (EGP) and Cori cycle activity provide insights into the maintenance of glycemic control in these animals. These parameter...
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Main Authors: | Margarida Coelho, Patricia Nunes, Vera M. Mendes, Bruno Manadas, Arend Heerschap, John G. Jones |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | Journal of Diabetes Research |
Online Access: | http://dx.doi.org/10.1155/2015/542029 |
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