Anticholinergic syndrome due to mydriatic drops intoxication in a child: A case report

Anticholinergic syndrome consists of neurological and systemic symptoms, including agitation, mydriasis and dryness that can be an adverse reaction to a number of medications, some of them as seemly harmless as cycloplegic mydriatic drops. We present the case of a 7-year-old previously healthy femal...

Full description

Saved in:
Bibliographic Details
Main Authors: J. Serralabós-Ferré, I. Barceló-Carceller
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750024002750
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1841545932554895360
author J. Serralabós-Ferré
I. Barceló-Carceller
author_facet J. Serralabós-Ferré
I. Barceló-Carceller
author_sort J. Serralabós-Ferré
collection DOAJ
description Anticholinergic syndrome consists of neurological and systemic symptoms, including agitation, mydriasis and dryness that can be an adverse reaction to a number of medications, some of them as seemly harmless as cycloplegic mydriatic drops. We present the case of a 7-year-old previously healthy female child who presented to the emergency room with impaired neurological status, inability to recognize family members and incoherent speech, as well as facial flushing, mucosal dryness and bilateral mydriasis after having mistakenly received a high dose of mydriatic drops. She made a complete recovery without need for treatment and had no sequelae. It has been described that anticholinergic syndrome can be related to a number of mydriatic drops (such as cyclopentolate) as well as other medications, in adults, children and neonates. It is a clinical diagnosis and requires no etiological testing. Depending on the severity at presentation, it may be required to administer the antidote physostigmine.
format Article
id doaj-art-b94e871712694020913f5d2e50ced06e
institution Kabale University
issn 2214-7500
language English
publishDate 2025-06-01
publisher Elsevier
record_format Article
series Toxicology Reports
spelling doaj-art-b94e871712694020913f5d2e50ced06e2025-01-11T06:41:29ZengElsevierToxicology Reports2214-75002025-06-0114101889Anticholinergic syndrome due to mydriatic drops intoxication in a child: A case reportJ. Serralabós-Ferré0I. Barceló-Carceller1Correspondence to: Hospital de la Santa Creu i Sant Pau, c/ Sant Antoni Maria Claret, 167, Barcelona 08025, Spain.; Pediatrics, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainPediatrics, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainAnticholinergic syndrome consists of neurological and systemic symptoms, including agitation, mydriasis and dryness that can be an adverse reaction to a number of medications, some of them as seemly harmless as cycloplegic mydriatic drops. We present the case of a 7-year-old previously healthy female child who presented to the emergency room with impaired neurological status, inability to recognize family members and incoherent speech, as well as facial flushing, mucosal dryness and bilateral mydriasis after having mistakenly received a high dose of mydriatic drops. She made a complete recovery without need for treatment and had no sequelae. It has been described that anticholinergic syndrome can be related to a number of mydriatic drops (such as cyclopentolate) as well as other medications, in adults, children and neonates. It is a clinical diagnosis and requires no etiological testing. Depending on the severity at presentation, it may be required to administer the antidote physostigmine.http://www.sciencedirect.com/science/article/pii/S2214750024002750Anticholinergic syndromeMydriatic dropsCyclopentolate intoxicationCase report
spellingShingle J. Serralabós-Ferré
I. Barceló-Carceller
Anticholinergic syndrome due to mydriatic drops intoxication in a child: A case report
Toxicology Reports
Anticholinergic syndrome
Mydriatic drops
Cyclopentolate intoxication
Case report
title Anticholinergic syndrome due to mydriatic drops intoxication in a child: A case report
title_full Anticholinergic syndrome due to mydriatic drops intoxication in a child: A case report
title_fullStr Anticholinergic syndrome due to mydriatic drops intoxication in a child: A case report
title_full_unstemmed Anticholinergic syndrome due to mydriatic drops intoxication in a child: A case report
title_short Anticholinergic syndrome due to mydriatic drops intoxication in a child: A case report
title_sort anticholinergic syndrome due to mydriatic drops intoxication in a child a case report
topic Anticholinergic syndrome
Mydriatic drops
Cyclopentolate intoxication
Case report
url http://www.sciencedirect.com/science/article/pii/S2214750024002750
work_keys_str_mv AT jserralabosferre anticholinergicsyndromeduetomydriaticdropsintoxicationinachildacasereport
AT ibarcelocarceller anticholinergicsyndromeduetomydriaticdropsintoxicationinachildacasereport