Prediction of Adverse Maternal Outcomes in Women with Early-Onset Preeclampsia with Severe Features in Mexico: Validation of the Full-PIERS Model

Objective. Validate the full-PIERS model in predicting adverse maternal outcomes in women with early-onset preeclampsia with severe features in our population. Methods. Retrospective cohort study. We applied the full-PIERS model on 130 women with severe early-onset preeclampsia who were treated at a...

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Main Authors: Eduardo Ponce Nájera, Marcela Montoya Hinojosa, Rogelio Armando Lozano Galván, Diego González Oropeza
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2024/5520312
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author Eduardo Ponce Nájera
Marcela Montoya Hinojosa
Rogelio Armando Lozano Galván
Diego González Oropeza
author_facet Eduardo Ponce Nájera
Marcela Montoya Hinojosa
Rogelio Armando Lozano Galván
Diego González Oropeza
author_sort Eduardo Ponce Nájera
collection DOAJ
description Objective. Validate the full-PIERS model in predicting adverse maternal outcomes in women with early-onset preeclampsia with severe features in our population. Methods. Retrospective cohort study. We applied the full-PIERS model on 130 women with severe early-onset preeclampsia who were treated at a second-level hospital in Nuevo León, México. We validated the full-PIERS model in its ability to discriminate through the AUROC. Results. The full-PIERS model applied to the data obtained in our study had good discrimination, revealing an AUC of 0.718 (95% CI 0.515–0.921; P=0.017). A cut-off of 7.95 was identified as the cut-off point with the best diagnostic performance, with the highest Youden index, presenting a sensitivity of 54.5% and specificity of 99.2% for the development of complications. Conclusion. The full-PIERS model can predict adverse maternal outcomes in women admitted to our hospital with severe early-onset preeclampsia within 48 hours of admission.
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series Obstetrics and Gynecology International
spelling doaj-art-b94bfc3505a6482ba50babd790e609132025-02-03T07:23:23ZengWileyObstetrics and Gynecology International1687-95972024-01-01202410.1155/2024/5520312Prediction of Adverse Maternal Outcomes in Women with Early-Onset Preeclampsia with Severe Features in Mexico: Validation of the Full-PIERS ModelEduardo Ponce Nájera0Marcela Montoya Hinojosa1Rogelio Armando Lozano Galván2Diego González Oropeza3Department of ObstetricsDepartment of ObstetricsHospital Zambrano Hellion TecSaludDepartment of ObstetricsObjective. Validate the full-PIERS model in predicting adverse maternal outcomes in women with early-onset preeclampsia with severe features in our population. Methods. Retrospective cohort study. We applied the full-PIERS model on 130 women with severe early-onset preeclampsia who were treated at a second-level hospital in Nuevo León, México. We validated the full-PIERS model in its ability to discriminate through the AUROC. Results. The full-PIERS model applied to the data obtained in our study had good discrimination, revealing an AUC of 0.718 (95% CI 0.515–0.921; P=0.017). A cut-off of 7.95 was identified as the cut-off point with the best diagnostic performance, with the highest Youden index, presenting a sensitivity of 54.5% and specificity of 99.2% for the development of complications. Conclusion. The full-PIERS model can predict adverse maternal outcomes in women admitted to our hospital with severe early-onset preeclampsia within 48 hours of admission.http://dx.doi.org/10.1155/2024/5520312
spellingShingle Eduardo Ponce Nájera
Marcela Montoya Hinojosa
Rogelio Armando Lozano Galván
Diego González Oropeza
Prediction of Adverse Maternal Outcomes in Women with Early-Onset Preeclampsia with Severe Features in Mexico: Validation of the Full-PIERS Model
Obstetrics and Gynecology International
title Prediction of Adverse Maternal Outcomes in Women with Early-Onset Preeclampsia with Severe Features in Mexico: Validation of the Full-PIERS Model
title_full Prediction of Adverse Maternal Outcomes in Women with Early-Onset Preeclampsia with Severe Features in Mexico: Validation of the Full-PIERS Model
title_fullStr Prediction of Adverse Maternal Outcomes in Women with Early-Onset Preeclampsia with Severe Features in Mexico: Validation of the Full-PIERS Model
title_full_unstemmed Prediction of Adverse Maternal Outcomes in Women with Early-Onset Preeclampsia with Severe Features in Mexico: Validation of the Full-PIERS Model
title_short Prediction of Adverse Maternal Outcomes in Women with Early-Onset Preeclampsia with Severe Features in Mexico: Validation of the Full-PIERS Model
title_sort prediction of adverse maternal outcomes in women with early onset preeclampsia with severe features in mexico validation of the full piers model
url http://dx.doi.org/10.1155/2024/5520312
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