“Can Vaginal Microbiota Act as a Biomarker for the Risk of Gynaecological Precancer and Cancer?”
Dear Editor, The female reproductive system hosts unique microbial communities that are crucial for maintaining women’s vaginal health and safeguarding the vaginal environment from numerous genitourinary infections [1,2]. The Vaginal Microbiota (VMB) interacts continuously with both the host and it...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2024-12-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/20370/74427_CE[Ra1]_F(SHU)_QC(AN_IS)_PF1(RI_SHU)_PFA(KM)_PN(IS).pdf |
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| _version_ | 1846128987723530240 |
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| author | Bhagyashri Patil Takbhate Swati Bhakare |
| author_facet | Bhagyashri Patil Takbhate Swati Bhakare |
| author_sort | Bhagyashri Patil Takbhate |
| collection | DOAJ |
| description | Dear Editor,
The female reproductive system hosts unique microbial communities that are crucial for maintaining women’s vaginal health and safeguarding the vaginal environment from numerous genitourinary infections [1,2]. The Vaginal Microbiota (VMB) interacts continuously with both the host and its surroundings, forming a complex system. Recently, the correlation between microbiota and various health conditions has gained considerable attention. While the gastrointestinal microbiota has been the primary focus, research has increasingly explored other areas of the body, including the female genital tract. Dysbiosis in the female genital tract, marked by an imbalance in microbial communities, has been identified as a potential contributor to several gynaecological disorders, like endometriosis, inflammatory diseases of the pelvis, Polycystic Ovary Syndrome (PCOS) and gynaecological malignancies [1]. Disruption of the VMB can trigger inflammation and weaken immune defences, potentially creating conditions conducive to cancer development. |
| format | Article |
| id | doaj-art-b94bbf14d0ac4b1b816edfc82b424e4f |
| institution | Kabale University |
| issn | 2249-782X 0973-709X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj-art-b94bbf14d0ac4b1b816edfc82b424e4f2024-12-10T11:29:47ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2024-12-011812010210.7860/JCDR/2024/74427.20370“Can Vaginal Microbiota Act as a Biomarker for the Risk of Gynaecological Precancer and Cancer?”Bhagyashri Patil Takbhate0Swati Bhakare 1Research Fellow, Department of Central Research Facility, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, Maharashtra, India.Senior Resident, Department of Obstetrics and Gynaecology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, Maharashtra, India.Dear Editor, The female reproductive system hosts unique microbial communities that are crucial for maintaining women’s vaginal health and safeguarding the vaginal environment from numerous genitourinary infections [1,2]. The Vaginal Microbiota (VMB) interacts continuously with both the host and its surroundings, forming a complex system. Recently, the correlation between microbiota and various health conditions has gained considerable attention. While the gastrointestinal microbiota has been the primary focus, research has increasingly explored other areas of the body, including the female genital tract. Dysbiosis in the female genital tract, marked by an imbalance in microbial communities, has been identified as a potential contributor to several gynaecological disorders, like endometriosis, inflammatory diseases of the pelvis, Polycystic Ovary Syndrome (PCOS) and gynaecological malignancies [1]. Disruption of the VMB can trigger inflammation and weaken immune defences, potentially creating conditions conducive to cancer development.https://www.jcdr.net/articles/PDF/20370/74427_CE[Ra1]_F(SHU)_QC(AN_IS)_PF1(RI_SHU)_PFA(KM)_PN(IS).pdfcervical cancerendometrial cancerlactobacilliovarian cancer |
| spellingShingle | Bhagyashri Patil Takbhate Swati Bhakare “Can Vaginal Microbiota Act as a Biomarker for the Risk of Gynaecological Precancer and Cancer?” Journal of Clinical and Diagnostic Research cervical cancer endometrial cancer lactobacilli ovarian cancer |
| title | “Can Vaginal Microbiota Act as a Biomarker for the Risk of Gynaecological Precancer and Cancer?” |
| title_full | “Can Vaginal Microbiota Act as a Biomarker for the Risk of Gynaecological Precancer and Cancer?” |
| title_fullStr | “Can Vaginal Microbiota Act as a Biomarker for the Risk of Gynaecological Precancer and Cancer?” |
| title_full_unstemmed | “Can Vaginal Microbiota Act as a Biomarker for the Risk of Gynaecological Precancer and Cancer?” |
| title_short | “Can Vaginal Microbiota Act as a Biomarker for the Risk of Gynaecological Precancer and Cancer?” |
| title_sort | can vaginal microbiota act as a biomarker for the risk of gynaecological precancer and cancer |
| topic | cervical cancer endometrial cancer lactobacilli ovarian cancer |
| url | https://www.jcdr.net/articles/PDF/20370/74427_CE[Ra1]_F(SHU)_QC(AN_IS)_PF1(RI_SHU)_PFA(KM)_PN(IS).pdf |
| work_keys_str_mv | AT bhagyashripatiltakbhate canvaginalmicrobiotaactasabiomarkerfortheriskofgynaecologicalprecancerandcancer AT swatibhakare canvaginalmicrobiotaactasabiomarkerfortheriskofgynaecologicalprecancerandcancer |