Host genetics maps to behaviour and brain structure in developmental mice

Host genetics maps to behaviour and brain structure in developmental mice

Abstract Gene-environment interactions in the postnatal period have a long-term impact on neurodevelopment. To effectively assess neurodevelopment in the mouse, we developed a behavioural pipeline that incorporates several validated behavioural tests to measure translationally relevant milestones of...

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Bibliographic Details
Main Authors: Sarah Asbury, Jonathan K. Y. Lai, Kelly C. Rilett, Zeeshan Haqqee, Benjamin C. Darwin, Jacob Ellegood, Jason P. Lerch, Jane A. Foster
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Behavioral and Brain Functions
Subjects:
Neurodevelopment
Structural MRI
Random forest
Machine learning
Early life stress
Online Access:https://doi.org/10.1186/s12993-024-00261-y
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