Adaptive laboratory-evolved MRSA with PPEF manifests cross-susceptibility to oxacillin and hypersensitivity to ciprofloxacin

Adaptive laboratory-evolved MRSA with PPEF manifests cross-susceptibility to oxacillin and hypersensitivity to ciprofloxacin

ABSTRACT Emerging resistance to current antibiotics is a global threat to human health. Therefore, comprehending the mechanism behind antibiotic resistance holds paramount importance. In the pursuit of finding new antibacterial agents, our group has developed a small molecule, PPEF (2′-(4-ethoxyphen...

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Bibliographic Details
Main Authors: Vikas Maurya, Raja Singh, Shruti Kutmutia, Bibha Chaudhary, Souvik Bhattacharjee, Vibha Tandon
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
antimicrobial resistance
PPEF
adaptive laboratory evolution
next-generation sequencing
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02974-24
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