Multi-trait association analysis reveals shared genetic loci between Alzheimer’s disease and cardiovascular traits

Multi-trait association analysis reveals shared genetic loci between Alzheimer’s disease and cardiovascular traits

Abstract Several cardiovascular traits and diseases co-occur with Alzheimer’s disease. We mapped their shared genetic architecture using multi-trait genome-wide association studies. Subsequent fine-mapping and colocalisation highlighted 16 genetic loci associated with both Alzheimer’s and cardiovasc...

Full description

Saved in:
Bibliographic Details
Main Authors: Fotios Koskeridis, Nurun Fancy, Pei Fang Tan, Devendra Meena, Evangelos Evangelou, Paul Elliott, Dennis Wang, Paul M. Matthews, Abbas Dehghan, Ioanna Tzoulaki
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53452-6
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items