CD73: agent development potential and its application in diabetes and atherosclerosis

CD73: agent development potential and its application in diabetes and atherosclerosis

CD73, an important metabolic and immune escape-promoting gene, catalyzes the hydrolysis of adenosine monophosphate (AMP) to adenosine (ADO). AMP has anti-inflammatory and vascular relaxant properties, while ADO has a strong immunosuppressive effect, suggesting that CD73 has pro-inflammatory and immu...

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Bibliographic Details
Main Authors: Dan Liu, Jingjing Zhao, Ling Li, Jie Wang, Chao Wang, Yudong Wu, Yucun Huang, Dongming Xing, Wujun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
CD73
circNT5E
diabetes
atherosclerosis
agent development
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1515875/full
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