Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatment
Abstract. Co-infection with hepatitis B virus (HBV) and human immunodeficiency virus (HIV) is common as the modes of disease transmission are similar. HIV affects the development of chronic HBV infection, leading to higher HBV DNA levels, cirrhosis, and end-stage liver duisease, and potentially lead...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Health - Lippincott Williams Wilkins
2025-01-01
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| Series: | Infectious Diseases & Immunity |
| Online Access: | http://journals.lww.com/10.1097/ID9.0000000000000123 |
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| author | Yaozu He Weiyin Lin Fei Gu Xianglong Lan Linghua Li Haijuan Wang |
| author_facet | Yaozu He Weiyin Lin Fei Gu Xianglong Lan Linghua Li Haijuan Wang |
| author_sort | Yaozu He |
| collection | DOAJ |
| description | Abstract. Co-infection with hepatitis B virus (HBV) and human immunodeficiency virus (HIV) is common as the modes of disease transmission are similar. HIV affects the development of chronic HBV infection, leading to higher HBV DNA levels, cirrhosis, and end-stage liver duisease, and potentially leading to hepatocellular carcinoma. One of the leading causes of mortality and morbidity in HIV-infected individualsis liver disease, despite the administration of antiretroviral therapy for HIV and HBV. Thus, the screening and follow-up of co-infected patients are vital formonitoring of liver disease progression. This study reviews the natural history and pathogenesis of liver disease in the context of HBV/HIV co-infection, current treatments for HBV in patients with HIV, and treatment outcomes in coinfected individuals. |
| format | Article |
| id | doaj-art-b7dcef4c39124a86ae7c7dbb111f9c01 |
| institution | Kabale University |
| issn | 2096-9511 2693-8839 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Health - Lippincott Williams Wilkins |
| record_format | Article |
| series | Infectious Diseases & Immunity |
| spelling | doaj-art-b7dcef4c39124a86ae7c7dbb111f9c012025-01-14T07:30:25ZengWolters Kluwer Health - Lippincott Williams WilkinsInfectious Diseases & Immunity2096-95112693-88392025-01-0151566110.1097/ID9.0000000000000123202501000-00006Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatmentYaozu He0Weiyin Lin1Fei Gu2Xianglong Lan3Linghua Li4Haijuan Wang1 Guangzhou Medical Research Institute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou 510060, China1 Guangzhou Medical Research Institute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou 510060, China1 Guangzhou Medical Research Institute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou 510060, China1 Guangzhou Medical Research Institute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou 510060, China1 Guangzhou Medical Research Institute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou 510060, ChinaAbstract. Co-infection with hepatitis B virus (HBV) and human immunodeficiency virus (HIV) is common as the modes of disease transmission are similar. HIV affects the development of chronic HBV infection, leading to higher HBV DNA levels, cirrhosis, and end-stage liver duisease, and potentially leading to hepatocellular carcinoma. One of the leading causes of mortality and morbidity in HIV-infected individualsis liver disease, despite the administration of antiretroviral therapy for HIV and HBV. Thus, the screening and follow-up of co-infected patients are vital formonitoring of liver disease progression. This study reviews the natural history and pathogenesis of liver disease in the context of HBV/HIV co-infection, current treatments for HBV in patients with HIV, and treatment outcomes in coinfected individuals.http://journals.lww.com/10.1097/ID9.0000000000000123 |
| spellingShingle | Yaozu He Weiyin Lin Fei Gu Xianglong Lan Linghua Li Haijuan Wang Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatment Infectious Diseases & Immunity |
| title | Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatment |
| title_full | Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatment |
| title_fullStr | Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatment |
| title_full_unstemmed | Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatment |
| title_short | Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatment |
| title_sort | co infection with hepatitis b and human immunodeficiency virus epidemiology pathogenesis and treatment |
| url | http://journals.lww.com/10.1097/ID9.0000000000000123 |
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