Preferences and uptake of home-based HIV self-testing for maternal retesting in Kenya.
<h4>Objective</h4>To compare preferences, uptake, and cofactors for unassisted home-based oral self-testing (HB-HIVST) versus clinic-based rapid diagnostic blood tests (CB-RDT) for maternal HIV retesting.<h4>Design</h4>Prospective cohort.<h4>Methods</h4>Between No...
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Public Library of Science (PLoS)
2024-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0302077 |
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| author | Alison L Drake Wenwen Jiang Peninah Kitao Shiza Farid Barbra A Richardson David A Katz Anjuli D Wagner Cheryl C Johnson Daniel Matemo GraceJohn Stewart John Kinuthia |
| author_facet | Alison L Drake Wenwen Jiang Peninah Kitao Shiza Farid Barbra A Richardson David A Katz Anjuli D Wagner Cheryl C Johnson Daniel Matemo GraceJohn Stewart John Kinuthia |
| author_sort | Alison L Drake |
| collection | DOAJ |
| description | <h4>Objective</h4>To compare preferences, uptake, and cofactors for unassisted home-based oral self-testing (HB-HIVST) versus clinic-based rapid diagnostic blood tests (CB-RDT) for maternal HIV retesting.<h4>Design</h4>Prospective cohort.<h4>Methods</h4>Between November 2017 and June 2019, HIV-negative pregnant Kenyan women receiving antenatal care were enrolled and given a choice to retest with HB-HIVST or CB-RDT. Women were asked to retest between 36 weeks gestation and 1-week post-delivery if the last HIV test was <24 weeks gestation or at 6 weeks postpartum if ≥24 weeks gestation, and self-report on retesting at a 14-week postpartum.<h4>Results</h4>Overall, 994 women enrolled and 33% (n = 330) selected HB-HIVST. HB-HIVST was selected because it was private (n = 224, 68%), convenient (n = 211, 63%), and offered flexibility in the timing of retesting (n = 207, 63%), whereas CB-RDT was selected due to the trust of providers to administer the test (n = 510, 77%) and convenience of clinic testing (n = 423, 64%). Among 905 women who reported retesting at follow-up, 135 (15%) used HB-HIVST. Most (n = 595, 94%) who selected CB-RDT retested with this strategy, compared to 39% (n = 120) who selected HB-HIVST retesting with HB-HIVST. HB-HIVST retesting was more common among women with higher household income and those who may have been unable to test during pregnancy (both retested postpartum and delivered <37 weeks gestation) and less common among women who were depressed. Most women said they would retest in the future using the test selected at enrollment (99% [n = 133] HB-HIVST; 93% [n = 715] CB-RDT-RDT).<h4>Conclusions</h4>While most women preferred CB-RDT for maternal retesting, HB-HIVST was acceptable and feasible and could be used to expand HIV retesting options. |
| format | Article |
| id | doaj-art-b7da8d85ec8b4f738f42c9f7483eae85 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-b7da8d85ec8b4f738f42c9f7483eae852024-12-04T05:31:16ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-01198e030207710.1371/journal.pone.0302077Preferences and uptake of home-based HIV self-testing for maternal retesting in Kenya.Alison L DrakeWenwen JiangPeninah KitaoShiza FaridBarbra A RichardsonDavid A KatzAnjuli D WagnerCheryl C JohnsonDaniel MatemoGraceJohn StewartJohn Kinuthia<h4>Objective</h4>To compare preferences, uptake, and cofactors for unassisted home-based oral self-testing (HB-HIVST) versus clinic-based rapid diagnostic blood tests (CB-RDT) for maternal HIV retesting.<h4>Design</h4>Prospective cohort.<h4>Methods</h4>Between November 2017 and June 2019, HIV-negative pregnant Kenyan women receiving antenatal care were enrolled and given a choice to retest with HB-HIVST or CB-RDT. Women were asked to retest between 36 weeks gestation and 1-week post-delivery if the last HIV test was <24 weeks gestation or at 6 weeks postpartum if ≥24 weeks gestation, and self-report on retesting at a 14-week postpartum.<h4>Results</h4>Overall, 994 women enrolled and 33% (n = 330) selected HB-HIVST. HB-HIVST was selected because it was private (n = 224, 68%), convenient (n = 211, 63%), and offered flexibility in the timing of retesting (n = 207, 63%), whereas CB-RDT was selected due to the trust of providers to administer the test (n = 510, 77%) and convenience of clinic testing (n = 423, 64%). Among 905 women who reported retesting at follow-up, 135 (15%) used HB-HIVST. Most (n = 595, 94%) who selected CB-RDT retested with this strategy, compared to 39% (n = 120) who selected HB-HIVST retesting with HB-HIVST. HB-HIVST retesting was more common among women with higher household income and those who may have been unable to test during pregnancy (both retested postpartum and delivered <37 weeks gestation) and less common among women who were depressed. Most women said they would retest in the future using the test selected at enrollment (99% [n = 133] HB-HIVST; 93% [n = 715] CB-RDT-RDT).<h4>Conclusions</h4>While most women preferred CB-RDT for maternal retesting, HB-HIVST was acceptable and feasible and could be used to expand HIV retesting options.https://doi.org/10.1371/journal.pone.0302077 |
| spellingShingle | Alison L Drake Wenwen Jiang Peninah Kitao Shiza Farid Barbra A Richardson David A Katz Anjuli D Wagner Cheryl C Johnson Daniel Matemo GraceJohn Stewart John Kinuthia Preferences and uptake of home-based HIV self-testing for maternal retesting in Kenya. PLoS ONE |
| title | Preferences and uptake of home-based HIV self-testing for maternal retesting in Kenya. |
| title_full | Preferences and uptake of home-based HIV self-testing for maternal retesting in Kenya. |
| title_fullStr | Preferences and uptake of home-based HIV self-testing for maternal retesting in Kenya. |
| title_full_unstemmed | Preferences and uptake of home-based HIV self-testing for maternal retesting in Kenya. |
| title_short | Preferences and uptake of home-based HIV self-testing for maternal retesting in Kenya. |
| title_sort | preferences and uptake of home based hiv self testing for maternal retesting in kenya |
| url | https://doi.org/10.1371/journal.pone.0302077 |
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