A novel approach to digital characterisation of Tertiary Lymphoid Structures in colorectal cancer

A novel approach to digital characterisation of Tertiary Lymphoid Structures in colorectal cancer

IntroductionTertiary Lymphoid Structures (TLS) in cancer tissue are potential sites for the organisation of immune responses to cancer, and correlate positively with improved clinical outcomes for patients including in colorectal cancer (CRC). However it has proven challenging to standardise assessm...

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Bibliographic Details
Main Authors:	Luis Munoz-Erazo, Saem Mul Park, Shelly Lin, Chun-Jen J. Chen, Lisa Y. Y. Zhou, Janet L. Rhodes, Taesung Jeon, Sonya Fenton, John L. McCall, Roslyn A. Kemp, P. Rod Dunbar
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Immunology
Subjects:	tertiary lymphoid structure colorectal cancer quantitative multiplex immunohistochemistry fluorescent multiplex IHC digital pathology
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1500792/full
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