Clinical impact of pharmacogenetic risk variants in a large chinese cohort

Clinical impact of pharmacogenetic risk variants in a large chinese cohort

Abstract Incorporating pharmacogenetics into clinical practice promises to improve therapeutic outcomes by optimizing drug selection and dosage based on genetic factors affecting drug response. A key advantage of PGx-guided therapy is to decrease the likelihood of adverse events. To evaluate the cli...

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Main Authors: Chun-Yu Wei, Ming-Shien Wen, Chih-Kuang Cheng, Yi-Jing Sheen, Tsung-Chieh Yao, Sing-Lian Lee, Jer-Yuarn Wu, Ming-Fang Tsai, Ling-Hui Li, Chun-houh Chen, Cathy S.-J. Fann, Hsin-Chou Yang, Yen-Tsung Huang, Hung-Hsin Chen, Yi-Min Liu, Erh-Chan Yeh, Yu-Ching Peng, Shuu-Jiun Wang, Shih-Pin Chen, Ming-Tsun Tsai, Teh-Ia Huo, Chien-Wei Su, Der-Cherng Tarng, Chin-Chou Huang, Jong-Ling Fuh, Keng-Hsin Lan, Yo-Tsen Liu, Ching-Liang Lu, Yi-Chung Lee, Yi-Hsiang Huang, Chung-Pin Li, Yen-Feng Wang, Yu-Cheng Hsieh, Yi-Ming Chen, Tzu-Hung Hsiao, Ching-Heng Lin, Yen-Ju Chen, I-Chieh Chen, Chien-Lin Mao, Shu-Jung Chang, Yen-Lin Chang, Yi-Ju Liao, Chih-Hung Lai, Wei-Ju Lee, Hsin Tung, Ting-Ting Yen, Hsin-Chien Yen, Jer-Hwa Chang, Chun-Yao Huang, Lung Chan, Yung-Wei Lin, Bu-Yuan Hsiao, Chaur-Jong Hu, Yung-Kuo Lin, Yung-Feng Lin, Tung-Cheng Chang, Deng-Chyang Wu, Jung-Yu Kan, Chung-Yao Hsu, Szu-Chia Chen, Ching-Chia Li, Chung-Feng Huang, Chau-Chyun Sheu, Lii-Jia Yang, Chung-Hwan Chen, Kuan-Mao Chen, Shu-Min Chang, Min-Shiuan Liou, Shi-Ping Wang, Kuan-Ting Lin, Hui-Ping Chuang, Ying-Ju Chen, Joey Sin, Ying-Ting Chen, Chiung-Chih Chang, Chang-Fu Kuo, Jing-Chi Lin, Ho-Chang Kuo, Tien-Min Chan, Chao-Wei Lee, Jenn-Haung Lai, Shue-Fen Luo, Hao-Tsai Cheng, Lian-Yu Lin, Li-Chun Chang, Chia-Ti Tsai, Hsien-Li Kao, Jian-Jyun Yu, Jiann-Shing Jeng, Min-Chin Chiu, Tzu-Chan Hong, Shun-Fa Yang, Hsueh-Ju Lu, Sheng-Chiang Su, Pauling Chu, Peng-Fei Li, Chia-Lin Tsai, Chia-Kuang Tsai, Shih-En Tang, Chien-Ming Lin, Yung-Fu Wu, Chih-Yang Huang, Shinn-Zong Ling, Chun-Chun Chang, Tzu-Kai Lin, Sheng-Mou Hsiao, Chih-Hung Chang, Chih-Dao Chen, Gwo-Chin Ma, Ting-Yu Chang, Juey-Jen Hwang, Chien-Lin Lu, Kuo-Jang Kao, Chen-Fang Hung, Shiou-Sheng Chen, Po-Yueh Chen, Kochung Tsui, Yuan-Tsong Chen, Chien-Hsiun Chen, Chih-Cheng Chien, Han-Sun Chiang, Yen-Ling Chiu, Hsiang-Cheng Chen, Pui-Yan Kwok
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61644-x
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