Accuracy of Individual Descriptors and Grading of Nodal Involvement by Axillary Ultrasound in Patients of Breast Cancer

Background. Four-node sampling is a useful substitute for sentinel node biopsy in low resource settings. USG is being increasingly used as a preoperative tool to evaluate axilla. We conducted this study to assess the accuracy of different descriptors of axillary ultrasound and to formulate a model o...

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Main Authors: Navneet Kaur, Pradeep Sharma, Akhil Garg, Anupama Tandon
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Breast Cancer
Online Access:http://dx.doi.org/10.1155/2013/930596
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author Navneet Kaur
Pradeep Sharma
Akhil Garg
Anupama Tandon
author_facet Navneet Kaur
Pradeep Sharma
Akhil Garg
Anupama Tandon
author_sort Navneet Kaur
collection DOAJ
description Background. Four-node sampling is a useful substitute for sentinel node biopsy in low resource settings. USG is being increasingly used as a preoperative tool to evaluate axilla. We conducted this study to assess the accuracy of different descriptors of axillary ultrasound and to formulate a model on grading of axillary involvement. Material and Methods. Thirty-four patients with clinically negative axilla underwent preoperative axillary ultrasound. The suspicious nodes were marked and details of various descriptors were noted. These nodes were sampled during axillary dissection and correlation of ultrasonographic findings with histopathological report was done to calculate accuracy of different descriptors. Based on this, a grading system of axillary lymph nodes involvement was formulated. Results. Based on the presence of various descriptors, five grades of nodal involvement could be defined. The most accurate descriptors to indicate nodal involvement were loss of hilar fat and hypoechoic internal echoes with specificity of 83% and positive predictive value of 92% each. The combination of descriptors of round shape with loss of hilar fat and hypoechoic internal echos had 100% specificity and positive predictive value. Conclusions. Grading of nodal involvement on axillary USG can be useful for selecting the most suspicious nodes for sampling during axillary dissection.
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spelling doaj-art-b786324c8fe940fdb3b35c8f0f9715dc2025-08-20T03:39:29ZengWileyInternational Journal of Breast Cancer2090-31702090-31892013-01-01201310.1155/2013/930596930596Accuracy of Individual Descriptors and Grading of Nodal Involvement by Axillary Ultrasound in Patients of Breast CancerNavneet Kaur0Pradeep Sharma1Akhil Garg2Anupama Tandon3Department of Surgery, University College of Medical Sciences & GTB Hospital, University of Delhi, Delhi 110095, IndiaDepartment of Surgery, University College of Medical Sciences & GTB Hospital, University of Delhi, Delhi 110095, IndiaDepartment of Surgery, University College of Medical Sciences & GTB Hospital, University of Delhi, Delhi 110095, IndiaDepartment of Radiology, University College of Medical Sciences & GTB Hospital, University of Delhi, Delhi 110095, IndiaBackground. Four-node sampling is a useful substitute for sentinel node biopsy in low resource settings. USG is being increasingly used as a preoperative tool to evaluate axilla. We conducted this study to assess the accuracy of different descriptors of axillary ultrasound and to formulate a model on grading of axillary involvement. Material and Methods. Thirty-four patients with clinically negative axilla underwent preoperative axillary ultrasound. The suspicious nodes were marked and details of various descriptors were noted. These nodes were sampled during axillary dissection and correlation of ultrasonographic findings with histopathological report was done to calculate accuracy of different descriptors. Based on this, a grading system of axillary lymph nodes involvement was formulated. Results. Based on the presence of various descriptors, five grades of nodal involvement could be defined. The most accurate descriptors to indicate nodal involvement were loss of hilar fat and hypoechoic internal echoes with specificity of 83% and positive predictive value of 92% each. The combination of descriptors of round shape with loss of hilar fat and hypoechoic internal echos had 100% specificity and positive predictive value. Conclusions. Grading of nodal involvement on axillary USG can be useful for selecting the most suspicious nodes for sampling during axillary dissection.http://dx.doi.org/10.1155/2013/930596
spellingShingle Navneet Kaur
Pradeep Sharma
Akhil Garg
Anupama Tandon
Accuracy of Individual Descriptors and Grading of Nodal Involvement by Axillary Ultrasound in Patients of Breast Cancer
International Journal of Breast Cancer
title Accuracy of Individual Descriptors and Grading of Nodal Involvement by Axillary Ultrasound in Patients of Breast Cancer
title_full Accuracy of Individual Descriptors and Grading of Nodal Involvement by Axillary Ultrasound in Patients of Breast Cancer
title_fullStr Accuracy of Individual Descriptors and Grading of Nodal Involvement by Axillary Ultrasound in Patients of Breast Cancer
title_full_unstemmed Accuracy of Individual Descriptors and Grading of Nodal Involvement by Axillary Ultrasound in Patients of Breast Cancer
title_short Accuracy of Individual Descriptors and Grading of Nodal Involvement by Axillary Ultrasound in Patients of Breast Cancer
title_sort accuracy of individual descriptors and grading of nodal involvement by axillary ultrasound in patients of breast cancer
url http://dx.doi.org/10.1155/2013/930596
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