HydroWrap for T2DM-Related Fractures: A smart H2S-delivery controller modulating Macrophage senescence

HydroWrap for T2DM-Related Fractures: A smart H2S-delivery controller modulating Macrophage senescence

Impaired fracture healing in type 2 diabetes mellitus (T2DM) poses a significant clinical challenge, primarily due to a compromised bone microenvironment driven by senescent macrophages and their amplifying effects. Reduced hydrogen sulfide (H2S) levels are a critical contributor to this pathology....

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Bibliographic Details
Main Authors:	Siqi Zhang, Hannan Cui, Jing Wang, Jie Zhou, Hongli Chen, Xinli Wang, Qian Yang, Jiahao Cao, Kaili Hao, Shanshan Fu, Wuyang Zhang, Xu Wang, Xinsen Lin, Xiqing Sun, Wei Lei, Tengjiao Wang, Yafei Feng
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2025-09-01
Series:	Bioactive Materials
Subjects:	Bone senescence Diabetic fracture healing Responsive hydrogel Photothermal therapy Hydrogen Sulfide
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452199X25001938
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