Multiple mechanisms of aminoglycoside ototoxicity are distinguished by subcellular localization of action
Mechanosensory hair cells of the inner ears and lateral line of vertebrates display heightened vulnerability to environmental insult, with damage resulting in hearing and balance disorders. An important example is hair cell loss due to exposure to toxic agents including therapeutic drugs such as the...
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Main Authors: | Patricia Wu, Francisco Barros-Becker, Roberto Ogelman, Esra D. Camci, Tor H. Linbo, Julian A. Simon, Edwin W. Rubel, David W. Raible |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2024-11-01
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Series: | Frontiers in Neurology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2024.1480435/full |
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