Gut dysbiosis is associated with difficult-to-treat rheumatoid arthritis

Gut dysbiosis is associated with difficult-to-treat rheumatoid arthritis

BackgroundDifficult-to-treat rheumatoid arthritis (D2T RA) refers to a subset of patients who fail to achieve adequate disease control after the use of two or more biological or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) with different mechanisms of action, while maintaini...

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Bibliographic Details
Main Authors: Patricia Ruiz-Limón, Natalia Mena-Vázquez, Isabel Moreno-Indias, Jose Manuel Lisbona-Montañez, Arkaitz Mucientes, Sara Manrique-Arija, Rocío Redondo-Rodriguez, Laura Cano-García, Francisco J. Tinahones, Antonio Fernández-Nebro
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
Subjects:
rheumatoid arthritis
gut microbiota
disease modifying antirheumatic drugs
Firmicutes/Bacteroidetes ratio
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1497756/full
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