Ultrasound-guided renal subcapsular transplantation of mesenchymal stem cells for treatment of acute kidney injury in a minipig model: safety and efficacy evaluation

Ultrasound-guided renal subcapsular transplantation of mesenchymal stem cells for treatment of acute kidney injury in a minipig model: safety and efficacy evaluation

Abstract Background Acute kidney injury (AKI) is a major global public health concern with limited treatment options. While preclinical studies have suggested the potential of mesenchymal stem cells (MSCs) to repair and protect injured kidneys in AKI, clinical trials using transarterial MSCs transpl...

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Bibliographic Details
Main Authors: Tuo Xiao, Yuhao Chen, Bo Jiang, Mengjie Huang, Yanjun Liang, Yue Xu, Xumin Zheng, Wenjuan Wang, Xiangmei Chen, Guangyan Cai
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Stem Cell Research & Therapy
Subjects:
Acute kidney injury
Cisplatin
Renal subcapsular transplantation
Ultrasound
Mesenchymal stem cells
Online Access:https://doi.org/10.1186/s13287-025-04137-4
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