Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis

Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis

Alzheimer’s disease (AD) is a complex neurodegenerative disorder, with amyloid-beta (Aβ) aggregation playing a key role in its pathogenesis. Aβ-induced oxidative stress leads to neuronal damage, mitochondrial dysfunction, and apoptosis, making antioxidative strategies promising for AD treatment. Thi...

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Bibliographic Details
Main Authors: Jiaxuan He, Peiye Xu, Ting Xu, Haiyang Yu, Lei Wang, Rongbing Chen, Kun Zhang, Yueliang Yao, Yanyan Xie, Qinsi Yang, Wei Wu, Da Sun, Dejun Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
zebrafish
hydrogen-rich water
behavior
antioxidant
reduced Aβ deposition
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1515092/full
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