Integrated analysis of single-cell RNA sequencing and bulk transcriptome data identifies a pyroptosis-associated diagnostic model for Parkinson’s disease

Integrated analysis of single-cell RNA sequencing and bulk transcriptome data identifies a pyroptosis-associated diagnostic model for Parkinson’s disease

Abstract Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by an insidious onset. Despite the emphasis on motor symptom-based diagnosis, there remains an unmet clinical need for effective diagnostic approaches during the prodromal phase of PD. Recent advances in sing...

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Bibliographic Details
Main Authors: Lin Wang, Yidan Qin, Jia Song, Jing Xu, Wei Quan, Hang Su, Huibin Zeng, Jian Zhang, Jia Li, Jiajun Chen
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Parkinson’s disease
Single cell RNA sequencing
Pyroptosis
Diagnostic model
Online Access:https://doi.org/10.1038/s41598-024-80185-9
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