Prevalence, patterns, and predictors of prescribing medications for opioid use disorder (MOUD) in the Inpatient setting

Background: There are many barriers to prescribing medications for opioid use disorder (MOUD). This study evaluates the prevalence, patterns, and predictors of inpatient MOUD prescribing at discharge to patients with a diagnosis of opioid use/opioid use disorder (OUD) that developed opioid withdrawa...

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Main Authors: Ashley Burke, Nina Vadiei, Lea Mollon
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Drug and Alcohol Dependence Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772724624000763
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author Ashley Burke
Nina Vadiei
Lea Mollon
author_facet Ashley Burke
Nina Vadiei
Lea Mollon
author_sort Ashley Burke
collection DOAJ
description Background: There are many barriers to prescribing medications for opioid use disorder (MOUD). This study evaluates the prevalence, patterns, and predictors of inpatient MOUD prescribing at discharge to patients with a diagnosis of opioid use/opioid use disorder (OUD) that developed opioid withdrawal during their hospital stay. Methods: This multicenter, retrospective cross-sectional study occurred at three hospitals in Arizona. Patients who developed opioid withdrawal during their hospitalization and had a documented opioid-related disorder between January 1, 2021, and January 1, 2022, were included in the study. Patient-specific factors were evaluated as predictors of MOUD prescribing at hospital discharge using descriptive, multivariate regression. Results: A total of 382 encounters were included; 249 had documented OUD (65.2 %), 75 of which were discharged with MOUD (75/249; 30.1 %). Patients with moderate/moderately severe opioid withdrawal had higher odds of being discharged with MOUD compared to those with mild opioid withdrawal (OR 2.87 [1.44–5.69], p=0.003). Patients admitted to the largest hospital in Phoenix had higher odds of being prescribed MOUD compared to the largest hospital in Tucson (OR 8.23 [3.02–22.49], p<0.001), as were patients who underwent a routine discharge compared to patient directed discharges (7.63 [2.35–24.71], p=0.001). Conclusions: Less than one-third of patients with OUD that developed opioid withdrawal during their hospitalization were prescribed MOUD at discharge. Treatment facility, opioid withdrawal severity, and discharge disposition were predictors of MOUD prescribing. Inpatient health-systems and policymakers may consider these data when developing policies/procedures aimed at increasing MOUD prescribing rates.
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spelling doaj-art-b698d918c9ea4238af93c3a8cb8f95e02024-12-12T05:24:28ZengElsevierDrug and Alcohol Dependence Reports2772-72462024-12-0113100292Prevalence, patterns, and predictors of prescribing medications for opioid use disorder (MOUD) in the Inpatient settingAshley Burke0Nina Vadiei1Lea Mollon2Banner – University Medical Center South, 2800 Ajo Way, Tucson, AZ 85713, United StatesThe University of Texas at Austin, College of Pharmacy, Division of Pharmacotherapy, 8403 Floyd Curl Dr, Austin, TX 78229, United States; Corresponding author.Banner – University Medical Center South, 2800 Ajo Way, Tucson, AZ 85713, United StatesBackground: There are many barriers to prescribing medications for opioid use disorder (MOUD). This study evaluates the prevalence, patterns, and predictors of inpatient MOUD prescribing at discharge to patients with a diagnosis of opioid use/opioid use disorder (OUD) that developed opioid withdrawal during their hospital stay. Methods: This multicenter, retrospective cross-sectional study occurred at three hospitals in Arizona. Patients who developed opioid withdrawal during their hospitalization and had a documented opioid-related disorder between January 1, 2021, and January 1, 2022, were included in the study. Patient-specific factors were evaluated as predictors of MOUD prescribing at hospital discharge using descriptive, multivariate regression. Results: A total of 382 encounters were included; 249 had documented OUD (65.2 %), 75 of which were discharged with MOUD (75/249; 30.1 %). Patients with moderate/moderately severe opioid withdrawal had higher odds of being discharged with MOUD compared to those with mild opioid withdrawal (OR 2.87 [1.44–5.69], p=0.003). Patients admitted to the largest hospital in Phoenix had higher odds of being prescribed MOUD compared to the largest hospital in Tucson (OR 8.23 [3.02–22.49], p<0.001), as were patients who underwent a routine discharge compared to patient directed discharges (7.63 [2.35–24.71], p=0.001). Conclusions: Less than one-third of patients with OUD that developed opioid withdrawal during their hospitalization were prescribed MOUD at discharge. Treatment facility, opioid withdrawal severity, and discharge disposition were predictors of MOUD prescribing. Inpatient health-systems and policymakers may consider these data when developing policies/procedures aimed at increasing MOUD prescribing rates.http://www.sciencedirect.com/science/article/pii/S2772724624000763Medications for opioid use disorderMOUDPrevalencePatternsPredictorsOpioid use disorder
spellingShingle Ashley Burke
Nina Vadiei
Lea Mollon
Prevalence, patterns, and predictors of prescribing medications for opioid use disorder (MOUD) in the Inpatient setting
Drug and Alcohol Dependence Reports
Medications for opioid use disorder
MOUD
Prevalence
Patterns
Predictors
Opioid use disorder
title Prevalence, patterns, and predictors of prescribing medications for opioid use disorder (MOUD) in the Inpatient setting
title_full Prevalence, patterns, and predictors of prescribing medications for opioid use disorder (MOUD) in the Inpatient setting
title_fullStr Prevalence, patterns, and predictors of prescribing medications for opioid use disorder (MOUD) in the Inpatient setting
title_full_unstemmed Prevalence, patterns, and predictors of prescribing medications for opioid use disorder (MOUD) in the Inpatient setting
title_short Prevalence, patterns, and predictors of prescribing medications for opioid use disorder (MOUD) in the Inpatient setting
title_sort prevalence patterns and predictors of prescribing medications for opioid use disorder moud in the inpatient setting
topic Medications for opioid use disorder
MOUD
Prevalence
Patterns
Predictors
Opioid use disorder
url http://www.sciencedirect.com/science/article/pii/S2772724624000763
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