Relationship between smoking and pulmonary tuberculosis based on positive sputum smears

Introduction: Smoking and tuberculosis are the two major, global health problems. Not only active smokers but also passive smokers are at risk of becoming infected with tuberculosis. Through many mechanisms, smoking decreases immunity and predisposes to numerous infections. This has a negative impac...

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Main Authors: Shinde, Mahesh, Dixit, Sangramsingh, Patel, Mihir, Sharma, Atharva, Satam, Juily, Patil, Yogeshwari, Upadhyay, Dheer, Chiwadshetti, Shreyasi, Mathur, Adhiraj, Rege, Varad, Kumari, Arunojya, Seth, Hiya
Format: Article
Language:deu
Published: German Medical Science GMS Publishing House 2024-11-01
Series:GMS Hygiene and Infection Control
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Online Access:http://www.egms.de/static/en/journals/dgkh/2024-19/dgkh000513.shtml
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author Shinde, Mahesh
Dixit, Sangramsingh
Patel, Mihir
Sharma, Atharva
Satam, Juily
Patil, Yogeshwari
Upadhyay, Dheer
Chiwadshetti, Shreyasi
Mathur, Adhiraj
Rege, Varad
Kumari, Arunojya
Seth, Hiya
author_facet Shinde, Mahesh
Dixit, Sangramsingh
Patel, Mihir
Sharma, Atharva
Satam, Juily
Patil, Yogeshwari
Upadhyay, Dheer
Chiwadshetti, Shreyasi
Mathur, Adhiraj
Rege, Varad
Kumari, Arunojya
Seth, Hiya
author_sort Shinde, Mahesh
collection DOAJ
description Introduction: Smoking and tuberculosis are the two major, global health problems. Not only active smokers but also passive smokers are at risk of becoming infected with tuberculosis. Through many mechanisms, smoking decreases immunity and predisposes to numerous infections. This has a negative impact on our health system. This knowledge of the association between smoking and tuberculosis can be utilized to develop a program for TB prevention and control.Method: This is a retrospective observational study carried out over a period of 18 months on 100 diagnosed cases of sputum smear-positive pulmonary tuberculosis patients undergoing treatment at Mumbai Maharashtra India as a part of the Revised National Tuberculosis Control Program (RNTCP).Results: 1+ sputum positivity was observed in a higher number of nonsmokers (77%) followed by ex-smokers (43%) and smokers (2%), 2 3+ sputum positivity was observed in a higher number of smokers (63% and 35%, respectively) followed by ex-smokers (29%) and nonsmokers (18% and 5%, respectively). Conclusion: Smokers demonstrated extensive infiltrates as compared to nonsmokers. Additionally, as the severity of smoking increased (smoking index), and the bacterial load also increased (higher grades of sputum positivity). Smokers also had poorer treatment outcomes than did nonsmokers.
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spelling doaj-art-b68d4b028b0a4b6a89c09db654d8800f2024-11-12T09:15:00ZdeuGerman Medical Science GMS Publishing HouseGMS Hygiene and Infection Control2196-52262024-11-0119Doc5810.3205/dgkh000513Relationship between smoking and pulmonary tuberculosis based on positive sputum smearsShinde, Mahesh0Dixit, Sangramsingh1Patel, Mihir2Sharma, Atharva3Satam, Juily4Patil, Yogeshwari5Upadhyay, Dheer6Chiwadshetti, Shreyasi7Mathur, Adhiraj8Rege, Varad9Kumari, Arunojya10Seth, Hiya11HBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaHBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaHBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaHBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaHBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaHBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaHBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaHBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaHBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaHBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaHBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaHBT Medical College and Dr. RN Cooper Hospital Juhu, Mumbai, IndiaIntroduction: Smoking and tuberculosis are the two major, global health problems. Not only active smokers but also passive smokers are at risk of becoming infected with tuberculosis. Through many mechanisms, smoking decreases immunity and predisposes to numerous infections. This has a negative impact on our health system. This knowledge of the association between smoking and tuberculosis can be utilized to develop a program for TB prevention and control.Method: This is a retrospective observational study carried out over a period of 18 months on 100 diagnosed cases of sputum smear-positive pulmonary tuberculosis patients undergoing treatment at Mumbai Maharashtra India as a part of the Revised National Tuberculosis Control Program (RNTCP).Results: 1+ sputum positivity was observed in a higher number of nonsmokers (77%) followed by ex-smokers (43%) and smokers (2%), 2 3+ sputum positivity was observed in a higher number of smokers (63% and 35%, respectively) followed by ex-smokers (29%) and nonsmokers (18% and 5%, respectively). Conclusion: Smokers demonstrated extensive infiltrates as compared to nonsmokers. Additionally, as the severity of smoking increased (smoking index), and the bacterial load also increased (higher grades of sputum positivity). Smokers also had poorer treatment outcomes than did nonsmokers.http://www.egms.de/static/en/journals/dgkh/2024-19/dgkh000513.shtmlsmokingpulmonary tuberculosissmoking indexnational tuberculosis control programdirectly observed treatmentdots
spellingShingle Shinde, Mahesh
Dixit, Sangramsingh
Patel, Mihir
Sharma, Atharva
Satam, Juily
Patil, Yogeshwari
Upadhyay, Dheer
Chiwadshetti, Shreyasi
Mathur, Adhiraj
Rege, Varad
Kumari, Arunojya
Seth, Hiya
Relationship between smoking and pulmonary tuberculosis based on positive sputum smears
GMS Hygiene and Infection Control
smoking
pulmonary tuberculosis
smoking index
national tuberculosis control program
directly observed treatment
dots
title Relationship between smoking and pulmonary tuberculosis based on positive sputum smears
title_full Relationship between smoking and pulmonary tuberculosis based on positive sputum smears
title_fullStr Relationship between smoking and pulmonary tuberculosis based on positive sputum smears
title_full_unstemmed Relationship between smoking and pulmonary tuberculosis based on positive sputum smears
title_short Relationship between smoking and pulmonary tuberculosis based on positive sputum smears
title_sort relationship between smoking and pulmonary tuberculosis based on positive sputum smears
topic smoking
pulmonary tuberculosis
smoking index
national tuberculosis control program
directly observed treatment
dots
url http://www.egms.de/static/en/journals/dgkh/2024-19/dgkh000513.shtml
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