The impact of door to extracorporeal cardiopulmonary resuscitation time on mortality and neurological outcomes among out-of-hospital cardiac arrest acute myocardial infarction patients treated by primary percutaneous coronary intervention
Background: Few previous studies evaluated the impact of time from the hospital arrival to the implementation of extracorporeal cardiopulmonary resuscitation (ECPR) (door to ECPR time) on outcomes among out-of-hospital cardiac arrest (OHCA) acute myocardial infarction (MI) patients. Methods: 50 pati...
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| Format: | Article |
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Elsevier
2024-11-01
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| Series: | American Heart Journal Plus |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666602224001162 |
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| author | Taro Takeuchi Yasunori Ueda Shumpei Kosugi Kuniyasu Ikeoka Haruya Yamane Takuya Ohashi Takashi Iehara Kazuho Ukai Kazuki Oozato Satoshi Oosaki Masayuki Nakamura Tatsuhisa Ozaki Tsuyoshi Mishima Haruhiko Abe Koichi Inoue Yasushi Matsumura |
| author_facet | Taro Takeuchi Yasunori Ueda Shumpei Kosugi Kuniyasu Ikeoka Haruya Yamane Takuya Ohashi Takashi Iehara Kazuho Ukai Kazuki Oozato Satoshi Oosaki Masayuki Nakamura Tatsuhisa Ozaki Tsuyoshi Mishima Haruhiko Abe Koichi Inoue Yasushi Matsumura |
| author_sort | Taro Takeuchi |
| collection | DOAJ |
| description | Background: Few previous studies evaluated the impact of time from the hospital arrival to the implementation of extracorporeal cardiopulmonary resuscitation (ECPR) (door to ECPR time) on outcomes among out-of-hospital cardiac arrest (OHCA) acute myocardial infarction (MI) patients. Methods: 50 patients with OHCA who received both ECPR and percutaneous coronary intervention (PCI) at Cardiovascular Division, NHO Osaka National Hospital were analyzed. Patients were divided into 2 groups according to the median of door to ECPR time. The primary outcome was all-cause death. Survival analyses were conducted to compare all-cause mortality at 90 days between 2 groups. Neurological outcome at 30 days was also compared between 2 groups using the Cerebral Performance Category (CPC). Results: The multivariable Cox proportional-hazards model showed that all-cause mortality at 90 days was significantly higher among patients with door to ECPR time ≥ 25 min compared with those with door to ECPR time < 25 min (adjusted hazard ratio [HR]: 3.14; 95 % confidence interval [CI]: 1.21–8.18). The proportion of patients with CPC at 30 days ≤ 2 was significantly higher among patients with shorter door to ECPR time (P = 0.048). Conclusion: Among patients with OHCA due to acute MI who received ECPR and PCI, the shorter door to ECPR time was associated with the lower mortality and favorable neurological outcomes. |
| format | Article |
| id | doaj-art-b68b3bb776504f5cb06c8d3561ecdcc7 |
| institution | Kabale University |
| issn | 2666-6022 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Heart Journal Plus |
| spelling | doaj-art-b68b3bb776504f5cb06c8d3561ecdcc72024-11-14T04:32:49ZengElsevierAmerican Heart Journal Plus2666-60222024-11-0147100473The impact of door to extracorporeal cardiopulmonary resuscitation time on mortality and neurological outcomes among out-of-hospital cardiac arrest acute myocardial infarction patients treated by primary percutaneous coronary interventionTaro Takeuchi0Yasunori Ueda1Shumpei Kosugi2Kuniyasu Ikeoka3Haruya Yamane4Takuya Ohashi5Takashi Iehara6Kazuho Ukai7Kazuki Oozato8Satoshi Oosaki9Masayuki Nakamura10Tatsuhisa Ozaki11Tsuyoshi Mishima12Haruhiko Abe13Koichi Inoue14Yasushi Matsumura15Cardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, Japan; Corresponding author at: Cardiovascular Division, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka 540-0006, Japan.Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanCardiovascular Division, NHO Osaka National Hospital, Osaka, JapanBackground: Few previous studies evaluated the impact of time from the hospital arrival to the implementation of extracorporeal cardiopulmonary resuscitation (ECPR) (door to ECPR time) on outcomes among out-of-hospital cardiac arrest (OHCA) acute myocardial infarction (MI) patients. Methods: 50 patients with OHCA who received both ECPR and percutaneous coronary intervention (PCI) at Cardiovascular Division, NHO Osaka National Hospital were analyzed. Patients were divided into 2 groups according to the median of door to ECPR time. The primary outcome was all-cause death. Survival analyses were conducted to compare all-cause mortality at 90 days between 2 groups. Neurological outcome at 30 days was also compared between 2 groups using the Cerebral Performance Category (CPC). Results: The multivariable Cox proportional-hazards model showed that all-cause mortality at 90 days was significantly higher among patients with door to ECPR time ≥ 25 min compared with those with door to ECPR time < 25 min (adjusted hazard ratio [HR]: 3.14; 95 % confidence interval [CI]: 1.21–8.18). The proportion of patients with CPC at 30 days ≤ 2 was significantly higher among patients with shorter door to ECPR time (P = 0.048). Conclusion: Among patients with OHCA due to acute MI who received ECPR and PCI, the shorter door to ECPR time was associated with the lower mortality and favorable neurological outcomes.http://www.sciencedirect.com/science/article/pii/S2666602224001162Extracorporeal cardiopulmonary resuscitationOut-of-hospital cardiac arrestMyocardial infarctionPercutaneous coronary intervention |
| spellingShingle | Taro Takeuchi Yasunori Ueda Shumpei Kosugi Kuniyasu Ikeoka Haruya Yamane Takuya Ohashi Takashi Iehara Kazuho Ukai Kazuki Oozato Satoshi Oosaki Masayuki Nakamura Tatsuhisa Ozaki Tsuyoshi Mishima Haruhiko Abe Koichi Inoue Yasushi Matsumura The impact of door to extracorporeal cardiopulmonary resuscitation time on mortality and neurological outcomes among out-of-hospital cardiac arrest acute myocardial infarction patients treated by primary percutaneous coronary intervention American Heart Journal Plus Extracorporeal cardiopulmonary resuscitation Out-of-hospital cardiac arrest Myocardial infarction Percutaneous coronary intervention |
| title | The impact of door to extracorporeal cardiopulmonary resuscitation time on mortality and neurological outcomes among out-of-hospital cardiac arrest acute myocardial infarction patients treated by primary percutaneous coronary intervention |
| title_full | The impact of door to extracorporeal cardiopulmonary resuscitation time on mortality and neurological outcomes among out-of-hospital cardiac arrest acute myocardial infarction patients treated by primary percutaneous coronary intervention |
| title_fullStr | The impact of door to extracorporeal cardiopulmonary resuscitation time on mortality and neurological outcomes among out-of-hospital cardiac arrest acute myocardial infarction patients treated by primary percutaneous coronary intervention |
| title_full_unstemmed | The impact of door to extracorporeal cardiopulmonary resuscitation time on mortality and neurological outcomes among out-of-hospital cardiac arrest acute myocardial infarction patients treated by primary percutaneous coronary intervention |
| title_short | The impact of door to extracorporeal cardiopulmonary resuscitation time on mortality and neurological outcomes among out-of-hospital cardiac arrest acute myocardial infarction patients treated by primary percutaneous coronary intervention |
| title_sort | impact of door to extracorporeal cardiopulmonary resuscitation time on mortality and neurological outcomes among out of hospital cardiac arrest acute myocardial infarction patients treated by primary percutaneous coronary intervention |
| topic | Extracorporeal cardiopulmonary resuscitation Out-of-hospital cardiac arrest Myocardial infarction Percutaneous coronary intervention |
| url | http://www.sciencedirect.com/science/article/pii/S2666602224001162 |
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