Novel Alzheimer’s disease risk variants identified based on whole-genome sequencing of APOE ε4 carriers

Novel Alzheimer’s disease risk variants identified based on whole-genome sequencing of APOE ε4 carriers

Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disease associated with a complex genetic etiology. Besides the apolipoprotein E ε4 (APOE ε4) allele, a few dozen other genetic loci associated with AD have been identified through genome-wide association studies (GWAS) conducted m...

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Main Authors: Jong-Ho Park, Inho Park, Emilia Moonkyung Youm, Sejoon Lee, June-Hee Park, Jongan Lee, Dong Young Lee, Min Soo Byun, Jun Ho Lee, Dahyun Yi, Sun Ju Chung, Kye Won Park, Nari Choi, Seong Yoon Kim, Woon Yoon, Hoyoung An, Ki woong Kim, Seong Hye Choi, Jee Hyang Jeong, Eun-Joo Kim, Hyojin Kang, Junehawk Lee, Younghoon Kim, Eunjung Alice Lee, Sang Won Seo, Duk L. Na, Jong-Won Kim
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01412-9
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