An enzyme-free electrochemical biosensor for sensitive and specific detection of microRNA-21 based on target recycling amplification and non-linear hybridization chain reaction
Abstract A novel electrochemical biosensor with high amplification efficiency was explored for serum microRNA-21 (miRNA-21) detection. This biosensor consisted of the target recycling amplification (TRA) and non-linear hybridization chain reaction (NHCR). When the target miRNA-21 was presented, hair...
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| Main Authors: | Jing Guo, Shou-feng Zhao, Shuang Chen, Wei-qing Song, Li-qun Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-06003-y |
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