Structural basis for Retriever-SNX17 assembly and endosomal sorting

Structural basis for Retriever-SNX17 assembly and endosomal sorting

Abstract During endosomal recycling, Sorting Nexin 17 (SNX17) facilitates the transport of numerous membrane cargo proteins by tethering them to the Retriever complex. Despite its importance, the mechanisms underlying this interaction have remained elusive. Here, we provide biochemical, structural,...

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Main Authors: Amika Singla, Daniel J. Boesch, Ho Yee Joyce Fung, Chigozie Ngoka, Avery S. Enriquez, Ran Song, Daniel A. Kramer, Yan Han, Esther Banarer, Andrew Lemoff, Puneet Juneja, Daniel D. Billadeau, Xiaochen Bai, Zhe Chen, Emre E. Turer, Ezra Burstein, Baoyu Chen
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54583-6
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https://doi.org/10.1038/s41467-024-54583-6

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