VALZ‐Pilot: High‐dose valacyclovir treatment in patients with early‐stage Alzheimer's disease
Abstract Introduction Herpes simplex virus (HSV) may be involved in Alzheimer's disease (AD) pathophysiology. The antiviral valacyclovir inhibits HSV replication. Methods This phase‐II pilot trial involved valacyclovir administration (thrice daily, 500 mg week 1, 1000 mg weeks 2–4) to persons a...
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| Main Authors: | Bodil Weidung, Eva‐Stina Hemmingsson, Jan Olsson, Torbjörn Sundström, Kaj Blennow, Henrik Zetterberg, Martin Ingelsson, Fredrik Elgh, Hugo Lövheim |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
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| Series: | Alzheimer’s & Dementia: Translational Research & Clinical Interventions |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/trc2.12264 |
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