The ribosome-associated quality control pathway supports survival in the absence of non-stop ribosome rescue factors

ABSTRACT In bacteria, if a ribosome translates an mRNA lacking a stop codon it becomes stalled at the 3′ end of the message. These ribosomes must be rescued by trans-translation or the alternative rescue factors (ArfA or ArfB). However, mounting evidence suggests that the ribosome quality control (R...

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Bibliographic Details
Main Authors: Katrina Callan, Cassidy R. Prince, Heather A. Feaga
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mBio
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Online Access:https://journals.asm.org/doi/10.1128/mbio.02322-24
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