Hippocampal Proliferation Is Increased in Presymptomatic Parkinson’s Disease and due to Microglia
Besides dopamine-deficiency related motor symptoms, nonmotor symptoms, including cognitive changes occur in Parkinson's disease (PD) patients, that may relate to accumulation of α-synuclein in the hippocampus (HC). This brain region also contains stem cells that can proliferate. This is a well-...
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Main Authors: | Karlijn J. Doorn, Benjamin Drukarch, Anne-Marie van Dam, Paul J. Lucassen |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2014/959154 |
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