Electrochemical Sensor Based on Co-MOF for the Detection of Dihydromyricetin in <i>Ampelopsis grossedentata</i>
Dihydromyricetin (DMY), as the main active ingredient in <i>Ampelopsis grossedentata</i>, is a naturally occurring flavonoid that has attracted extensive attention for its multiple biological activities. For the quick and accurate measurement of DMY, a novel electrochemical sensor based...
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2025-01-01
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| author | Xiaojing Si Yue Huang Mei Han Liqiang Luo |
| author_facet | Xiaojing Si Yue Huang Mei Han Liqiang Luo |
| author_sort | Xiaojing Si |
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| description | Dihydromyricetin (DMY), as the main active ingredient in <i>Ampelopsis grossedentata</i>, is a naturally occurring flavonoid that has attracted extensive attention for its multiple biological activities. For the quick and accurate measurement of DMY, a novel electrochemical sensor based on a glassy carbon electrode (GCE) modified with a cobalt metal-organic framework (Co-MOF) was proposed in this work. The Co-MOF was synthesized via a single-step hydrothermal process using Co(NO<sub>3</sub>)<sub>2</sub>·6H<sub>2</sub>O. Fourier infrared spectroscopy, X-ray photoelectron spectroscopy and scanning electron microscopy were used to study the morphology and structure of the synthesized Co-MOF. Utilizing differential pulse voltammetry and cyclic voltammetry methods, the effectiveness of DMY electro-oxidation on the Co-MOF/GCE was examined. The results showed that, in comparison to the bare GCE, the electro-oxidation peak current of DMY was considerably increased by the Co-MOF/GCE. The detection limit was 0.07 μM, and the peak current demonstrated two linear relationships in the ranges of 0.2−20 μM and 20−100 μM, with the linear equations of Ip (μA) = 0.4729c (μM) + 1.0822 (R<sup>2</sup> = 0.9913) and Ip (μA) = 0.0939c (μM) + 8.4178 (R<sup>2</sup> = 0.9971), respectively. The average DMY content in <i>Ampelopsis grossedentata</i> samples was measured to be 3.275 μM, with a good recovery of 108.27% and a relative standard deviation value of 3.46%. The proposed method is simple, rapid and sensitive and can be used for the determination of DMY in <i>Ampelopsis grossedentata</i>. |
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| institution | Kabale University |
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| language | English |
| publishDate | 2025-01-01 |
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| series | Molecules |
| spelling | doaj-art-b55149fff63b4aab94546d21cb2fc1182025-01-10T13:19:07ZengMDPI AGMolecules1420-30492025-01-0130118010.3390/molecules30010180Electrochemical Sensor Based on Co-MOF for the Detection of Dihydromyricetin in <i>Ampelopsis grossedentata</i>Xiaojing Si0Yue Huang1Mei Han2Liqiang Luo3Department of Food Science, Shanghai Business School, Shanghai 200235, ChinaDepartment of Food Science, Shanghai Business School, Shanghai 200235, ChinaDepartment of Food Science, Shanghai Business School, Shanghai 200235, ChinaCollege of Sciences, Shanghai University, Shanghai 200444, ChinaDihydromyricetin (DMY), as the main active ingredient in <i>Ampelopsis grossedentata</i>, is a naturally occurring flavonoid that has attracted extensive attention for its multiple biological activities. For the quick and accurate measurement of DMY, a novel electrochemical sensor based on a glassy carbon electrode (GCE) modified with a cobalt metal-organic framework (Co-MOF) was proposed in this work. The Co-MOF was synthesized via a single-step hydrothermal process using Co(NO<sub>3</sub>)<sub>2</sub>·6H<sub>2</sub>O. Fourier infrared spectroscopy, X-ray photoelectron spectroscopy and scanning electron microscopy were used to study the morphology and structure of the synthesized Co-MOF. Utilizing differential pulse voltammetry and cyclic voltammetry methods, the effectiveness of DMY electro-oxidation on the Co-MOF/GCE was examined. The results showed that, in comparison to the bare GCE, the electro-oxidation peak current of DMY was considerably increased by the Co-MOF/GCE. The detection limit was 0.07 μM, and the peak current demonstrated two linear relationships in the ranges of 0.2−20 μM and 20−100 μM, with the linear equations of Ip (μA) = 0.4729c (μM) + 1.0822 (R<sup>2</sup> = 0.9913) and Ip (μA) = 0.0939c (μM) + 8.4178 (R<sup>2</sup> = 0.9971), respectively. The average DMY content in <i>Ampelopsis grossedentata</i> samples was measured to be 3.275 μM, with a good recovery of 108.27% and a relative standard deviation value of 3.46%. The proposed method is simple, rapid and sensitive and can be used for the determination of DMY in <i>Ampelopsis grossedentata</i>.https://www.mdpi.com/1420-3049/30/1/180dihydromyricetindeterminationelectrochemical sensormetal-organic framework<i>Ampelopsis grossedentata</i> |
| spellingShingle | Xiaojing Si Yue Huang Mei Han Liqiang Luo Electrochemical Sensor Based on Co-MOF for the Detection of Dihydromyricetin in <i>Ampelopsis grossedentata</i> Molecules dihydromyricetin determination electrochemical sensor metal-organic framework <i>Ampelopsis grossedentata</i> |
| title | Electrochemical Sensor Based on Co-MOF for the Detection of Dihydromyricetin in <i>Ampelopsis grossedentata</i> |
| title_full | Electrochemical Sensor Based on Co-MOF for the Detection of Dihydromyricetin in <i>Ampelopsis grossedentata</i> |
| title_fullStr | Electrochemical Sensor Based on Co-MOF for the Detection of Dihydromyricetin in <i>Ampelopsis grossedentata</i> |
| title_full_unstemmed | Electrochemical Sensor Based on Co-MOF for the Detection of Dihydromyricetin in <i>Ampelopsis grossedentata</i> |
| title_short | Electrochemical Sensor Based on Co-MOF for the Detection of Dihydromyricetin in <i>Ampelopsis grossedentata</i> |
| title_sort | electrochemical sensor based on co mof for the detection of dihydromyricetin in i ampelopsis grossedentata i |
| topic | dihydromyricetin determination electrochemical sensor metal-organic framework <i>Ampelopsis grossedentata</i> |
| url | https://www.mdpi.com/1420-3049/30/1/180 |
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