The Combined Inhibition of SREBP and mTORC1 Signaling Synergistically Inhibits B‐Cell Lymphoma
ABSTRACT Background The sterol regulatory element‐binding protein (SREBP) pathway is essential for maintaining sterol homeostasis during B cell activation and germinal center B cell proliferation. However, its potential as a therapeutic target to treat B‐cell lymphoma remains unclear. Methods We exa...
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| Main Authors: | Zhenhan Zhu, Wenxia Jiang, Jiehao Zhou, Alexander Robert Maldeney, Jingru Liang, Jing Yang, Wei Luo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-11-01
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| Series: | Cancer Medicine |
| Online Access: | https://doi.org/10.1002/cam4.70342 |
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